Nigericin

尼日利亚菌素

Also known as: Nigericin sodium salt, Antibiotic K178, Azalomycin M, Helixin C, Polyetherin A, X-464, Helix c, Aids003767, NIGERICIN NA

Nigericin (CAS 28380-24-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C40H68O11 and a molecular weight of 746.943 g/mol. It is also known as Nigericin sodium salt, Antibiotic K178 and Azalomycin M. Key properties include a melting point of 245-255ºC, a boiling point of 779.9ºC at 760mmHg, a density of 1.19g/cm3 and a flash point of 226.9ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 28380-24-7
Jingsj CID: J-1963061-6
Molecular Formula: C₄₀H₆₈O₁₁
Chinese Name: 尼日利亚菌素
Molecular Weight: 746.943 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	245-255ºC
Boiling Point	779.9ºC at 760mmHg
Density	1.19g/cm3
Flash Point	226.9ºC
Exact Mass	746.458130
PSA	145.20000
LogP	4.37090
Refractive Index	1.543
Storage Conditions	2-8°C

Activity & Biological Data

Target	K+/H+ ionophore[1]
Additional Information	[1]. Zotova L, et al. Novel components of an active mitochondrial K(+)/H(+) exchange. J Biol Chem. 2010 May 7;285(19):14399-414. [2]. Mariathasan S, et al.Cryopyrin activates the inflammasome in response to toxins and ATP.Nature. 2006 Mar 9;440(7081):228-32. [3]. Bissinger R, et al. Triggering of Suicidal Erythrocyte Death by the Antibiotic Ionophore Nigericin. Basic Clin Pharmacol Toxicol. 2016 May;118(5):381-9.

Target

K+/H+ ionophore[1]

Additional Information

[1]. Zotova L, et al. Novel components of an active mitochondrial K(+)/H(+) exchange. J Biol Chem. 2010 May 7;285(19):14399-414. [2]. Mariathasan S, et al.Cryopyrin activates the inflammasome in response to toxins and ATP.Nature. 2006 Mar 9;440(7081):228-32. [3]. Bissinger R, et al. Triggering of Suicidal Erythrocyte Death by the Antibiotic Ionophore Nigericin. Basic Clin Pharmacol Toxicol. 2016 May;118(5):381-9.

Frequently Asked Questions

What is the CAS number of Nigericin?

The CAS number of Nigericin is 28380-24-7.

What are the molecular formula and molecular weight of Nigericin?

Nigericin has molecular formula C40H68O11 and molecular weight 746.943 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Nigericin (CAS 28380-24-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963061-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.