Tyrphostin A1

Also known as: 2-[(4-Methoxyphenyl)methylidene]propanedinitrile, (4-Methoxybenzylidene)malononitrile, 2-(4-Methoxybenzylidene)malononitrile, AG 9, Tyrphostin 1, Tyrphostin AG 9, p-Methoxybenzylidenemalononitrile, 2-[(4-Methoxyphenyl)methylene]malononitrile

Tyrphostin A1 (CAS 2826-26-8) is a compound in the Aliphatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C11H8N2O and a molecular weight of 184.19400 g/mol. Key properties include a melting point of 113-116ºC(lit.), a boiling point of 352.4ºC at 760mmHg, a density of 1.169g/cm3 and a flash point of 148.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 2826-26-8
Jingsj CID: J-25413-5
Molecular Formula: C₁₁H₈N₂O
Molecular Weight: 184.19400 g/mol
Category: Aliphatic Hydrocarbons
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	113-116ºC(lit.)
Boiling Point	352.4ºC at 760mmHg
Density	1.169g/cm3
Flash Point	148.8ºC
Exact Mass	184.06400
PSA	56.81000
LogP	2.12576
Vapor Pressure	3.85E-05mmHg at 25°C
Refractive Index	1.589
Additional Property	chloroform: soluble50mg/mL, clear, light yellow

Activity & Biological Data

Additional Information	[1]. Du C, et al. Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice. J Neuroimmunol. 2001 Mar 1;114(1-2):69-79. [2]. Ogura T, et al. Activation of background membrane conductance by the tyrosine kinase inhibitor tyrphostin A23 and its inactive analog tyrphostin A1 in guinea pig ventricular myocytes. Jpn J Pharmacol. 2001 Nov;87(3):235-9.

Additional Information

[1]. Du C, et al. Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice. J Neuroimmunol. 2001 Mar 1;114(1-2):69-79. [2]. Ogura T, et al. Activation of background membrane conductance by the tyrosine kinase inhibitor tyrphostin A23 and its inactive analog tyrphostin A1 in guinea pig ventricular myocytes. Jpn J Pharmacol. 2001 Nov;87(3):235-9.

Customs & Trade Information

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Tyrphostin A1?

The CAS number of Tyrphostin A1 is 2826-26-8.

What are the molecular formula and molecular weight of Tyrphostin A1?

Tyrphostin A1 has molecular formula C11H8N2O and molecular weight 184.19400 g/mol.

What are the upstream and downstream products of Tyrphostin A1?

For Tyrphostin A1, Upstream Products: 4-Methoxybenzaldehyde, Malononitrile, Dibromomalononitrile; Downstream Products: 2-(4-METHOXYBENZYL)MALONONITRILE, Diethyl 2,6-dimethylpyridine-3,5-dicarboxylate, 2-(4-Methoxyphenyl)-1H-benzimidazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tyrphostin A1 (CAS 2826-26-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25413-5 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.