Gambogic Acid
藤黄酸
Also known as: β-Guttiferrin, β-Guttilactone, Guttatic acid, Guttific acid, Gambogic acid, (2Z)-2-Methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-buten-1-yl)-11-(4-methyl-3-penten-1-yl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-2-butenoic acid
Gambogic Acid (CAS 2752-65-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C38H44O8 and a molecular weight of 628.751 g/mol. It is also known as β-Guttiferrin, β-Guttilactone and Guttatic acid. Key properties include a melting point of 88.5°C, a boiling point of 808.9±65.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 251.4±27.8 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 2752-65-0
- Jingsj CID
- J-1975659-2
- Molecular Formula
- C38H44O8
- Chinese Name
- 藤黄酸
- Molecular Weight
- 628.751 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 88.5°C |
|---|---|
| Boiling Point | 808.9±65.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 251.4±27.8 °C |
| Exact Mass | 628.303589 |
| PSA | 119.36000 |
| LogP | 10.30 |
| Vapor Pressure | 0.0±3.0 mmHg at 25°C |
| Refractive Index | 1.627 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Bcl-B:0.66 μM (IC50) Mcl-1:0.79 μM (IC50) Bfl-1:1.06 μM (IC50) Bcl-2:1.21 μM (IC50) Bcl-xL:1.47 μM (IC50) Bcl-W:2.02 μM (IC50) Autophagy |
|---|---|
| Additional Information | [1]. Zhai D, et al. Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins. Mol Cancer Ther. 2008 Jun;7(6):1639-46. [2]. Wang LH, et al. Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling. Br J Cancer. 2014 Jan 21;110(2):341-52. |
Customs & Trade Information
| HS Code | 2942000000 |
|---|
Frequently Asked Questions
What is the CAS number of Gambogic Acid?
The CAS number of Gambogic Acid is 2752-65-0.
What are the molecular formula and molecular weight of Gambogic Acid?
Gambogic Acid has molecular formula C38H44O8 and molecular weight 628.751 g/mol.
Is Gambogic Acid hazardous?
Gambogic Acid has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Gambogic Acid (CAS 2752-65-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975659-2 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.