Zotepine
佐替平
Also known as: 2-[(8-Chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine, Lodopin, Nipolept, Zoleptil, Setous, Zotepina, Zotepinum, 2-Chloro-11-(2-dimethylaminoethoxy)dibenzo[b,f]thiepine, 2-[(3-chloro-5-benzo[b][1]benzothiepinyl)oxy]-N,N-dimethylethanamine, Compound-4, UNII-U29O83JAZW
Zotepine (CAS 26615-21-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H18ClNOS and a molecular weight of 331.86 g/mol. It is also known as 2-[(8-Chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine, Lodopin and Nipolept. Key properties include a melting point of 90-91 °C, a boiling point of 478.4±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 243.2±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 26615-21-4
- Jingsj CID
- J-1969495-3
- Molecular Formula
- C18H18ClNOS
- Chinese Name
- 佐替平
- Molecular Weight
- 331.86 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 90-91 °C |
|---|---|
| Boiling Point | 478.4±45.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 243.2±28.7 °C |
| Exact Mass | 331.079773 |
| PSA | 37.77000 |
| LogP | 6.57 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.656 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H400 — Very toxic to aquatic life
Activity & Biological Data
| Additional Information | [1]. Richelson E, et, al. Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci. 2000 Nov 24;68(1):29-39. [2]. Yamamura S, et, al. Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex. Br J Pharmacol. 2009 Jun;157(4):656-65. |
|---|
Frequently Asked Questions
What is the CAS number of Zotepine?
The CAS number of Zotepine is 26615-21-4.
What are the molecular formula and molecular weight of Zotepine?
Zotepine has molecular formula C18H18ClNOS and molecular weight 331.86 g/mol.
Is Zotepine hazardous?
Zotepine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H400 — Very toxic to aquatic life.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Zotepine (CAS 26615-21-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1969495-3 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.