Sodium chenodeoxycholate
鹅去氧胆酸钠
Also known as: Chenodeoxycholic acid sodium salt, Sodium chenodesoxycholate, 3α,7α-Dihydroxy-5β-cholan-24-oic acid sodium salt, 3α,7α-Dihydroxy-5β-cholanic acid sodium salt, 5β-Cholanic acid-3α,7α-diol sodium salt, Chenodiol sodium, Chenodesoxycholic acid sodium salt, Cholan-24-oic acid, 3,7-dihydroxy-, monosodium salt, (3α,5β,7α)-, NSC 681066
Sodium chenodeoxycholate (CAS 2646-38-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C24H39NaO4 and a molecular weight of 414.55 g/mol. It is also known as Chenodeoxycholic acid sodium salt, Sodium chenodesoxycholate and 3α,7α-Dihydroxy-5β-cholan-24-oic acid sodium salt. Key properties include a melting point of 298 °C(dec.), a boiling point of 547.1ºC at 760mmHg and a flash point of 298.8ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 2646-38-0
- Jingsj CID
- J-25428-1
- Molecular Formula
- C24H39NaO4
- Chinese Name
- 鹅去氧胆酸钠
- Molecular Weight
- 414.55 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 298 °C(dec.) |
|---|---|
| Boiling Point | 547.1ºC at 760mmHg |
| Flash Point | 298.8ºC |
| Exact Mass | 414.274597 |
| PSA | 80.59000 |
| LogP | 3.14320 |
| Vapor Pressure | 2.98E-14mmHg at 25°C |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
- H332 — Harmful if inhaled
- H351 — Suspected of causing cancer
Activity & Biological Data
| Additional Information | [1]. Stauffer AT, et al. Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. J Biol Chem. 2002 Jul 19;277(29):26286-92 [2]. Noh K, et al. Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β. Drug Metab [3]. Casaburi I, et al. Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation. Cell Cycle. 2012 Jul 15;11(14):2699-710 [4]. Ao M, et al. Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells. Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C447-56 [5]. Kawabe Y, et al. The molecular mechanism of the induction of the low density lipoprotein receptor by chenodeoxycholic acid in cultured human cells. Biochem Biophys Res Commun. 1995 Mar 8;208(1):405-11. |
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Frequently Asked Questions
What is the CAS number of Sodium chenodeoxycholate?
The CAS number of Sodium chenodeoxycholate is 2646-38-0.
What are the molecular formula and molecular weight of Sodium chenodeoxycholate?
Sodium chenodeoxycholate has molecular formula C24H39NaO4 and molecular weight 414.55 g/mol.
Is Sodium chenodeoxycholate hazardous?
Sodium chenodeoxycholate has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Sodium chenodeoxycholate (CAS 2646-38-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25428-1 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.