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Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate

Also known as: ZPCK, (3S)-3-benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanone, (S)-(1-benzyl-3-chloro-2-oxopropyl)carbamic acid benzyl ester, Benzyl [(1S)-1-benzyl-3-chloro-2-oxopropyl]carbamate, Benzyl [(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]carbamate, Carbamic acid, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, Carbamic acid, [3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, (S)-, EINECS 247-432-8, L-Carbobenzyloxyphenylalanyl chloromethyl ketone, MFCD00037114, N-CBZ-L-phenylalanine chloromethyl ketone, N-Carbobenzoxy-L-phenylalanyl-chloromethyl ketone, N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone, N-[(1S)-3-Chloro-2-Oxo-1-(Phenylmethyl)Propyl]-Carbamic Acid Phenylmethyl Ester, N-benzyloxycarbonyl-L-phenylalanine chloromethyl ketone, Z-L-Phe chloromethyl ketone, Z-Phe-CH2Cl, Z-Phe-CMK, benzyl (S)-(1-benzyl-3-chloro-2-oxopropyl)carbamate, Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate

Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate (CAS 26049-94-5) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C18H18ClNO3 and a molecular weight of 331.793 g/mol. Key properties include a melting point of 107-108ºC(lit.), a boiling point of 503.1±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 258.1±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
26049-94-5
Jingsj CID
J-1991211-9
Molecular Formula
C18H18ClNO3
Molecular Weight
331.793 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point107-108ºC(lit.)
Boiling Point503.1±50.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point258.1±30.1 °C
Exact Mass331.097534
PSA55.40000
LogP4.28
Vapor Pressure0.0±1.3 mmHg at 25°C
Refractive Index1.573

GHS Safety & Compliance

CorrosionSignal word: Danger
  • H314 — Causes severe skin burns and eye damage

Activity & Biological Data

Additional Information[1]. Zhao C, et al. Pharmacokinetics and metabolism of SL-01, a prodrug of gemcitabine, in rats. Cancer Chemother Pharmacol. 2013 Jun;71(6):1541-50.

Customs & Trade Information

HS Code2924299090
Summary2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate?

The CAS number of Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate is 26049-94-5.

What are the molecular formula and molecular weight of Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate?

Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate has molecular formula C18H18ClNO3 and molecular weight 331.793 g/mol.

Is Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate hazardous?

Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate has GHS signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage.

What are the upstream and downstream products of Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate?

For Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate, Upstream Products: Chloroiodomethane, N-Benzyloxycarbonyl-L-phenylalanine ethyl ester, N-Benzyloxycarbonyl-L-phenylalanine; Downstream Products: (2S,3S)-3-(Benzyloxycarbonylamino)-1-chloro-2-hydroxy-4-phenylbutane, (2S,3S)-1,2-Epoxy-3-(Cbz-amino)-4-phenylbutane.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate (CAS 26049-94-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1991211-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.