1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
Also known as: EDC·HCl, EDC hydrochloride, EDAC, EDCI, WSC hydrochloride, 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide hydrochloride, N-[3-(Dimethylamino)propyl]-N'-ethylcarbodiimide hydrochloride, 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide monohydrochloride, 3-(Ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine hydrochloride, N'-(Ethylcarbonimidoyl)-N,N-dimethyl-1,3-propanediamine hydrochloride
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (CAS 25952-53-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H18ClN3 and a molecular weight of 191.70 g/mol. Key properties include a melting point of 110-115 °C(lit.), a boiling point of 269.1ºC at 760 mmHg, a density of 0.877 g/mL at 20 °C(lit.) and a flash point of 107.9ºC. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H318 — Causes serious eye damage and H335 — May cause respiratory irritation. It is listed by 2 suppliers, 1 of which publish reference prices, from 22.61 to 69.40 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 25952-53-8
- Jingsj CID
- J-1111270-3
- Molecular Formula
- C8H18ClN3
- Molecular Weight
- 191.70 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | >98.0%(T) 250g | ¥5,652.00 | $3.38 /gBest ¥22.61/g CNY | CN China MOQ 250g | |
In Stock | >98.0%(T) 25g | ¥1,071.00 | $6.41 /g ¥42.84/g CNY | CN China MOQ 25g | |
In Stock | >98.0%(T) 5g | ¥347.00 | $10.39 /g ¥69.40/g CNY | CN China MOQ 5g |
Physicochemical Properties
| Melting Point | 110-115 °C(lit.) |
|---|---|
| Boiling Point | 269.1ºC at 760 mmHg |
| Density | 0.877 g/mL at 20 °C(lit.) |
| Flash Point | 107.9ºC |
| Exact Mass | 191.118927 |
| PSA | 27.96000 |
| LogP | 1.93390 |
| Vapor Pressure | 0.171mmHg at 25°C |
| Refractive Index | n20/D 1.461 |
| Storage Conditions | −20°C |
| Stability | Stable, but sensitive to moisture. Incompatible with strong acids, strong oxidizing agents, moisture. |
| Additional Property | Soluble |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H318 — Causes serious eye damage
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Kunihiko Seno, et al. Spectrophotometric determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow injection analysis. Anal Sci. 2008 Apr;24(4):505-8. [2]. Kunihiko Seno, et al. Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine. Anal Sci. 2009 Mar;25(3):389-93. [3]. Runqiang Yang, et al. AMADH inhibitor optimization and its effects on GABA accumulation in soybean sprouts under NaCl-CaCl 2 treatment. 3 Biotech. 2019 May;9(5):184. |
|---|
Customs & Trade Information
| HS Code | 2925290090 |
|---|---|
| Summary | 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride?
The CAS number of 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is 25952-53-8.
What are the molecular formula and molecular weight of 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride?
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride has molecular formula C8H18ClN3 and molecular weight 191.70 g/mol.
Which suppliers offer 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride?
2 supplier(s) listed; reference unit price ¥22.61–69.40 /g.
Is 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride hazardous?
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H318 — Causes serious eye damage; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride?
For 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, Downstream Products: 4-Biphenylcarboxylic acid, Cabergoline, 1-[3-(Dimethylamino)propyl]-3-ethylurea.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (CAS 25952-53-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1111270-3 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.