Doxorubicin hydrochloride
盐酸阿霉素
Also known as: Adriamycin hydrochloride, Doxorubicin HCl, ADM hydrochloride, ADR, Hydroxydaunorubicin hydrochloride, 14-Hydroxydaunomycin hydrochloride, DOX HCl, Rubex, Adriblastina hydrochloride
Doxorubicin hydrochloride (CAS 25316-40-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C27H30ClNO11 and a molecular weight of 579.980 g/mol. It is also known as Adriamycin hydrochloride, Doxorubicin HCl and ADM hydrochloride. Key properties include a melting point of 216ºC, a boiling point of 810.3ºC at 760 mmHg and a flash point of 443.8ºC. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 25316-40-9
- Jingsj CID
- J-22743-8
- Molecular Formula
- C27H30ClNO11
- Chinese Name
- 盐酸阿霉素
- Molecular Weight
- 579.980 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 216ºC |
|---|---|
| Boiling Point | 810.3ºC at 760 mmHg |
| Flash Point | 443.8ºC |
| Exact Mass | 579.150757 |
| PSA | 206.07000 |
| LogP | 1.50360 |
| Vapor Pressure | 9.64E-28mmHg at 25°C |
| Storage Conditions | 2-8℃ |
| Additional Property | H2O: 10 mg/mL, clear, red-orange |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H350 — May cause cancer
Activity & Biological Data
| Target | Topoisomerase II |
|---|---|
| Additional Information | [1]. Nitiss JL, et al. Targeting DNA topoisomerase II in cancer chemotherapy.Nat Rev Cancer. 2009 May;9(5):338-50. [2]. Sadeghi-Aliabadi H, et al. Cytotoxic evaluation of doxorubicin in combination with simvastatin against human cancer cells. Res Pharm Sci. 2010 Jul;5(2):127-33. [3]. El-Zawahry A, et al. Doxorubicin increases the effectiveness of Apo2L/TRAIL for tumor growth inhibition of prostate cancerxenografts. BMC Cancer. 2005 Jan 7;5:2. [4]. Hayward R, et al. Doxorubicin cardiotoxicity in the rat: an in vivo characterization. J Am Assoc Lab Anim Sci. 2007 Jul;46(4):20-32. |
Customs & Trade Information
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Doxorubicin hydrochloride?
The CAS number of Doxorubicin hydrochloride is 25316-40-9.
What are the molecular formula and molecular weight of Doxorubicin hydrochloride?
Doxorubicin hydrochloride has molecular formula C27H30ClNO11 and molecular weight 579.980 g/mol.
Is Doxorubicin hydrochloride hazardous?
Doxorubicin hydrochloride has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Doxorubicin hydrochloride?
For Doxorubicin hydrochloride, Upstream Products: Daunorubicin hydrochloride; Downstream Products: Doxorubicin, Doxorubicinone, Leurubicin.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Doxorubicin hydrochloride (CAS 25316-40-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-22743-8 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.