Catharanthine

Also known as: (+)-3,4-Didehydrocoronaridine, Ibogamine-18-carboxylic acid, 3,4-didehydro-, methyl ester, (2α,5β,6α,18β)-, Catharanthin, Methyl (2α,5β,18β)-3,4-didehydroibogamine-18-carboxylate

Catharanthine (CAS 2468-21-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C21H24N2O2 and a molecular weight of 336.427 g/mol. Key properties include a melting point of 138-140ºC, a boiling point of 491.5±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 251.1±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 2468-21-5
Jingsj CID: J-1971790-9
Molecular Formula: C₂₁H₂₄N₂O₂
Molecular Weight: 336.427 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	138-140ºC
Boiling Point	491.5±45.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	251.1±28.7 °C
Exact Mass	336.183777
PSA	45.33000
LogP	4.05
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.663

Activity & Biological Data

Additional Information	[1]. Pereira, D.M., et al., Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission. Phytomedicine, 2010. 17(8-9): p. 646-52. [2]. Prakash, V. and S.N. Timasheff, Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline. Biochemistry, 1991. 30(3): p. 873-80. [3]. Williams, J.A., Catharanthine: a novel stimulator of pancreatic enzyme release. Cell Tissue Res, 1978. 192(2): p. 277-84. [4]. Arias, H.R., et al., Catharanthine alkaloids are noncompetitive antagonists of muscle-type nicotinic acetylcholine receptors. Neurochem Int, 2010. 57(2): p. 153-61.

Additional Information

[1]. Pereira, D.M., et al., Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission. Phytomedicine, 2010. 17(8-9): p. 646-52. [2]. Prakash, V. and S.N. Timasheff, Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline. Biochemistry, 1991. 30(3): p. 873-80. [3]. Williams, J.A., Catharanthine: a novel stimulator of pancreatic enzyme release. Cell Tissue Res, 1978. 192(2): p. 277-84. [4]. Arias, H.R., et al., Catharanthine alkaloids are noncompetitive antagonists of muscle-type nicotinic acetylcholine receptors. Neurochem Int, 2010. 57(2): p. 153-61.

Frequently Asked Questions

What is the CAS number of Catharanthine?

The CAS number of Catharanthine is 2468-21-5.

What are the molecular formula and molecular weight of Catharanthine?

Catharanthine has molecular formula C21H24N2O2 and molecular weight 336.427 g/mol.

What are the upstream and downstream products of Catharanthine?

For Catharanthine, Upstream Products: Indole-3-acetic acid; Downstream Products: 3',4'-Anhydrovinblastine, Leurosine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Catharanthine (CAS 2468-21-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971790-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.