Acetylshikonin

乙酰紫草素

Also known as: Acetylshikonin, Shikonin acetate, O-Acetylshikonin, (R)-1-(5,8-Dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl acetate, 2-[(R)-1-Acetoxy-4-methyl-3-pentenyl]-5,8-dihydroxy-1,4-naphthoquinone, Nsc110199, MFCD00143538

Acetylshikonin (CAS 24502-78-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H18O6 and a molecular weight of 330.332 g/mol. It is also known as Shikonin acetate, O-Acetylshikonin and (R)-1-(5,8-Dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl acetate. Key properties include a melting point of 86°C, a boiling point of 553.2±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 201.3±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 24502-78-1
Jingsj CID: J-18832-2
Molecular Formula: C₁₈H₁₈O₆
Chinese Name: 乙酰紫草素
Molecular Weight: 330.332 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	86°C
Boiling Point	553.2±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	201.3±23.6 °C
Exact Mass	330.110352
PSA	100.90000
LogP	4.57
Vapor Pressure	0.0±1.6 mmHg at 25°C
Refractive Index	1.602

Activity & Biological Data

Target	IC50: 1.4-4.0 μM (all P450s)[2] AChE[3]
Additional Information	[1]. Park SH, et al. Identification of acetylshikonin as the novel CYP2J2 inhibitor with anti-cancer activity in HepG2 cells. Phytomedicine. 2017 Jan 15;24:134-140. [2]. Shon JC, et al. Acetylshikonin is a novel non-selective cytochrome P450 inhibitor. Biopharm Drug Dispos. 2017 Dec;38(9):553-556. [3]. Wang Y, et al. Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells. Evid Based Complement Alternat Med. 2013;2013:937370.

Target

IC50: 1.4-4.0 μM (all P450s)[2] AChE[3]

Additional Information

[1]. Park SH, et al. Identification of acetylshikonin as the novel CYP2J2 inhibitor with anti-cancer activity in HepG2 cells. Phytomedicine. 2017 Jan 15;24:134-140. [2]. Shon JC, et al. Acetylshikonin is a novel non-selective cytochrome P450 inhibitor. Biopharm Drug Dispos. 2017 Dec;38(9):553-556. [3]. Wang Y, et al. Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells. Evid Based Complement Alternat Med. 2013;2013:937370.

Frequently Asked Questions

What is the CAS number of Acetylshikonin?

The CAS number of Acetylshikonin is 24502-78-1.

What are the molecular formula and molecular weight of Acetylshikonin?

Acetylshikonin has molecular formula C18H18O6 and molecular weight 330.332 g/mol.

What are the upstream and downstream products of Acetylshikonin?

For Acetylshikonin, Upstream Products: Shikonin, acetic acid; Downstream Products: Shikonin.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Acetylshikonin (CAS 24502-78-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18832-2 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.