Daunorubicin hydrochloride

盐酸柔红霉素

Also known as: Daunorubicin HCl, Daunomycin hydrochloride, Cerubidine, Daunoblastina, Daunomycin HCl, Rubidomycin hydrochloride, Ondena, RP 13057 hydrochloride, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-, hydrochloride (1:1), (8S,10S)-8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride, Daunomycin, monohydrochloride, Daunorubicin.HCl, daunoblastin, daunomycinchlorohydrate, ndc0082-4155, ondena, rp13057hydrochloride, rubidomycinhydrochloride

Daunorubicin hydrochloride (CAS 23541-50-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C27H30ClNO10 and a molecular weight of 563.981 g/mol. It is also known as Daunorubicin HCl, Daunomycin hydrochloride and Cerubidine. Key properties include a melting point of 188 - 190ºC, a boiling point of 770ºC at 760 mmHg and a flash point of 419.5ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H334 — May cause allergy or asthma symptoms if inhaled and H351 — Suspected of causing cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 23541-50-6
Jingsj CID: J-204-6
Molecular Formula: C₂₇H₃₀ClNO₁₀
Chinese Name: 盐酸柔红霉素
Molecular Weight: 563.981 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	188 - 190ºC
Boiling Point	770ºC at 760 mmHg
Flash Point	419.5ºC
Exact Mass	563.155823
PSA	185.84000
LogP	2.53120
Vapor Pressure	6.99E-26mmHg at 25°C

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger

H301 — Toxic if swallowed
H334 — May cause allergy or asthma symptoms if inhaled
H351 — Suspected of causing cancer

Activity & Biological Data

Target	Topoisomerase II
Additional Information	[1]. Lehmann M, et al. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environ Mol Mutagen. 2004;43(4):250-7. [2]. Svensson SP, et al. Melanin inhibits cytotoxic effects of Doxorubicin and Daunorubicin in MOLT 4 cells. Pigment Cell Res. 2003 Aug;16(4):351-4 [3]. Gervasoni JE Jr, et al. An effective in vitro antitumor response against human pancreatic carcinoma with paclitaxel and Daunorubicin by induction of both necrosis and apoptosis. Anticancer Res. 2004 Sep-Oct;24(5A):2617-26 [4]. Arozal W, et al. Telmisartan prevents the progression of renal injury in daunorubicin rats with the alteration of angiotensin II and endothelin-1 receptor expression associated with its PPAR-γ agonist actions. Toxicology. 2011 Jan 11;279(1-3):91-9.

Target

Topoisomerase II

Additional Information

[1]. Lehmann M, et al. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environ Mol Mutagen. 2004;43(4):250-7. [2]. Svensson SP, et al. Melanin inhibits cytotoxic effects of Doxorubicin and Daunorubicin in MOLT 4 cells. Pigment Cell Res. 2003 Aug;16(4):351-4 [3]. Gervasoni JE Jr, et al. An effective in vitro antitumor response against human pancreatic carcinoma with paclitaxel and Daunorubicin by induction of both necrosis and apoptosis. Anticancer Res. 2004 Sep-Oct;24(5A):2617-26 [4]. Arozal W, et al. Telmisartan prevents the progression of renal injury in daunorubicin rats with the alteration of angiotensin II and endothelin-1 receptor expression associated with its PPAR-γ agonist actions. Toxicology. 2011 Jan 11;279(1-3):91-9.

Customs & Trade Information

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Daunorubicin hydrochloride?

The CAS number of Daunorubicin hydrochloride is 23541-50-6.

What are the molecular formula and molecular weight of Daunorubicin hydrochloride?

Daunorubicin hydrochloride has molecular formula C27H30ClNO10 and molecular weight 563.981 g/mol.

Is Daunorubicin hydrochloride hazardous?

Daunorubicin hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H334 — May cause allergy or asthma symptoms if inhaled; H351 — Suspected of causing cancer.

What are the upstream and downstream products of Daunorubicin hydrochloride?

For Daunorubicin hydrochloride, Upstream Products: Zorubicin hydrochloride; Downstream Products: Daunorubicin, Idarubicin, Idarubicin hydrochloride.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Daunorubicin hydrochloride (CAS 23541-50-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-204-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.