1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride

1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐

Also known as: MPTP hydrochloride, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (1:1), 1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine hydrochloride, 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine hydrochloride, Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl-, hydrochloride (1:1), Pyridine, 1,2,5,6-tetrahydro-1-methyl-4-phenyl-, hydrochloride

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (CAS 23007-85-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C12H16ClN and a molecular weight of 209.715 g/mol. It is also known as MPTP hydrochloride, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride and 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (1:1). Key properties include a melting point of 254 - 257 °C, a boiling point of 258.6ºC at 760mmHg and a flash point of 105.8ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H311 — Toxic in contact with skin and H331 — Toxic if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 23007-85-4
Jingsj CID: J-1986879-8
Molecular Formula: C₁₂H₁₆ClN
Chinese Name: 1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐
Molecular Weight: 209.715 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	254 - 257 °C
Boiling Point	258.6ºC at 760mmHg
Flash Point	105.8ºC
Exact Mass	209.097122
PSA	3.24000
LogP	3.14540
Vapor Pressure	0.0136mmHg at 25°C

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed
H311 — Toxic in contact with skin
H331 — Toxic if inhaled
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information	[1]. Langston J W, Irwin I. MPTP Neurotoxicity: An Overview and Characterization of Phases of Toxicity. II. Selective Accumulation of MPP in the Substantia Nigra: A Key to Neurotoxicity (Question). Life Sci., 1985, 36, No. 3, 201-12. [2]. Desole M S, et al. Further investigation of allopurinol effects on MPTP-induced oxidative stress in the striatum and brain stem of the rat. Source:Pharmacol.Biochem.Behav., 1996, 54, No. 2, 377-83. [3]. Hsu K S, et al. Potentiation of MPTP by 4-Phenylpyridine on the Neuromuscular Blockade in Mouse Phrenic Nerve-Diaphragm. Neuropharmacology, 1993, 32, No. 9, 877-83. [4]. Sun XL, et al. Gas1 up-regulation is inducible and contributes to cell apoptosis in reactive astrocytes in the substantia nigra of LPS and MPTP models. J Neuroinflammation. 2016 Jul 8;13(1):180.

Additional Information

[1]. Langston J W, Irwin I. MPTP Neurotoxicity: An Overview and Characterization of Phases of Toxicity. II. Selective Accumulation of MPP in the Substantia Nigra: A Key to Neurotoxicity (Question). Life Sci., 1985, 36, No. 3, 201-12. [2]. Desole M S, et al. Further investigation of allopurinol effects on MPTP-induced oxidative stress in the striatum and brain stem of the rat. Source:Pharmacol.Biochem.Behav., 1996, 54, No. 2, 377-83. [3]. Hsu K S, et al. Potentiation of MPTP by 4-Phenylpyridine on the Neuromuscular Blockade in Mouse Phrenic Nerve-Diaphragm. Neuropharmacology, 1993, 32, No. 9, 877-83. [4]. Sun XL, et al. Gas1 up-regulation is inducible and contributes to cell apoptosis in reactive astrocytes in the substantia nigra of LPS and MPTP models. J Neuroinflammation. 2016 Jul 8;13(1):180.

Customs & Trade Information

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride?

The CAS number of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride is 23007-85-4.

What are the molecular formula and molecular weight of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride?

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride has molecular formula C12H16ClN and molecular weight 209.715 g/mol.

Is 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride hazardous?

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H311 — Toxic in contact with skin; H331 — Toxic if inhaled.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (CAS 23007-85-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986879-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.