Neferine
Also known as: Methylliensinine, 4''-O-Methylliensinine, Neferin, 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
Neferine (CAS 2292-16-2) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C38H44N2O6 and a molecular weight of 624.766 g/mol. Key properties include a boiling point of 710.9±60.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 383.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 2292-16-2
- Jingsj CID
- J-1972683-6
- Molecular Formula
- C38H44N2O6
- Molecular Weight
- 624.766 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 710.9±60.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 383.8±32.9 °C |
| Exact Mass | 624.319946 |
| PSA | 72.86000 |
| LogP | 5.49 |
| Appearance | white to beige |
| Vapor Pressure | 0.0±2.4 mmHg at 25°C |
| Refractive Index | 1.601 |
| Storage Conditions | 2-8°C |
| Additional Property | DMSO: >15mg/mL |
Activity & Biological Data
| Target | p65 Autophagy |
|---|---|
| Additional Information | [1]. Baskaran R, et al. Neferine prevents NF-κB translocation and protects muscle cells from oxidative stress and apoptosis induced by hypoxia. Biofactors. 2016 Jul 8;42(4):407-17. [2]. Liu X, et al. Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice. Oncotarget. 2016 Sep 20;7(38):61703-61715. |
Frequently Asked Questions
What is the CAS number of Neferine?
The CAS number of Neferine is 2292-16-2.
What are the molecular formula and molecular weight of Neferine?
Neferine has molecular formula C38H44N2O6 and molecular weight 624.766 g/mol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Neferine (CAS 2292-16-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1972683-6 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.