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Silver sulfadiazine

Also known as: Silvadene, Flamazine, Sulfadiazine silver, Silver sulfadiazinate, Silver sulphadiazine, Dermazin, Thermazene, Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, silver(1+) salt

Silver sulfadiazine (CAS 22199-08-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H9AgN4O2S and a molecular weight of 357.137 g/mol. Key properties include a melting point of 285 °C (dec.)(lit.), a boiling point of 512.6ºC at 760 mmHg, a density of 1.496g/cm3 and a flash point of 263.8ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
22199-08-2
Jingsj CID
J-48263-3
Molecular Formula
C10H9AgN4O2S
Molecular Weight
357.137 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point285 °C (dec.)(lit.)
Boiling Point512.6ºC at 760 mmHg
Density1.496g/cm3
Flash Point263.8ºC
Exact Mass355.949707
PSA94.32000
LogP3.11490
Vapor Pressure1.28E-10mmHg at 25°C

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Strydom SJ, et al. Poly(amidoamine) dendrimer-mediated synthesis and stabilization of silver sulfonamide nanoparticles with increased antibacterial activity. Nanomedicine. 2013;9(1):85-93. [2]. Munhoz DR, et al. Alginate films functionalized with silver sulfadiazine-loaded [Mg-Al] layered double hydroxide as antimicrobial wound dressing. Int J Biol Macromol. 2019;141:504-510.

Customs & Trade Information

HS Code2935001000

Frequently Asked Questions

What is the CAS number of Silver sulfadiazine?

The CAS number of Silver sulfadiazine is 22199-08-2.

What are the molecular formula and molecular weight of Silver sulfadiazine?

Silver sulfadiazine has molecular formula C10H9AgN4O2S and molecular weight 357.137 g/mol.

Is Silver sulfadiazine hazardous?

Silver sulfadiazine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Silver sulfadiazine (CAS 22199-08-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48263-3 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.