Tretazicar

曲他齐卡

Also known as: CB-1954, CB 1954, 5-(1-Aziridinyl)-2,4-dinitrobenzamide, 5-(Aziridin-1-yl)-2,4-dinitrobenzamide, 5-Aziridino-2,4-dinitrobenzamide, NSC 115829, 2,4-Dinitro-5-(aziridine-1-yl)benzamide, 2,4-Dinitro-5-ethyleneiminobenzamide, 5-(Aziridin-1-yl)-2,4-dinitrobenzamide, 5-aziridino-2,4-dinitrobenzamide

Tretazicar (CAS 21919-05-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H8N4O5 and a molecular weight of 252.184 g/mol. It is also known as CB-1954, CB 1954 and 5-(1-Aziridinyl)-2,4-dinitrobenzamide. Key properties include a melting point of 173 °C, a boiling point of 427.2±45.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 212.2±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 21919-05-1
Jingsj CID: J-1968861-9
Molecular Formula: C₉H₈N₄O₅
Chinese Name: 曲他齐卡
Molecular Weight: 252.184 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	173 °C
Boiling Point	427.2±45.0 °C at 760 mmHg
Density	1.7±0.1 g/cm3
Flash Point	212.2±28.7 °C
Exact Mass	252.049469
PSA	137.74000
LogP	1.28
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.715

Activity & Biological Data

Additional Information	[1]. Knox RJ,et al. Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy. Cancer Res. 2000 Aug 1;60(15):4179-86. [2]. Knox RJ, et al. CB 1954: from the Walker tumor to NQO2 and VDEPT. Curr Pharm Des. 2003;9(26):2091-104. [3]. Green NK, et al. Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronicadenovirus vector. Int J Cancer. 2003 Mar 10;104(1):104-12. [4]. Drabek D, et al. The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954. Gene Ther. 1997 Feb;4(2):93-100.

Additional Information

[1]. Knox RJ,et al. Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy. Cancer Res. 2000 Aug 1;60(15):4179-86. [2]. Knox RJ, et al. CB 1954: from the Walker tumor to NQO2 and VDEPT. Curr Pharm Des. 2003;9(26):2091-104. [3]. Green NK, et al. Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronicadenovirus vector. Int J Cancer. 2003 Mar 10;104(1):104-12. [4]. Drabek D, et al. The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954. Gene Ther. 1997 Feb;4(2):93-100.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Tretazicar?

The CAS number of Tretazicar is 21919-05-1.

What are the molecular formula and molecular weight of Tretazicar?

Tretazicar has molecular formula C9H8N4O5 and molecular weight 252.184 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tretazicar (CAS 21919-05-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1968861-9 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.