1-Methyl-L-tryptophan

1-甲基-L-色氨酸

Also known as: (S)-Indoximod, (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, L-1-Methyltryptophan, H-Trp(1-Me)-OH, L-Tryptophan, 1-methyl-, MFCD00467133

1-Methyl-L-tryptophan (CAS 21339-55-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C12H14N2O2 and a molecular weight of 218.252 g/mol. It is also known as (S)-Indoximod, (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid and L-1-Methyltryptophan. Key properties include a melting point of 223-226 ºC, a boiling point of 429.3±35.0 °C at 760 mmHg, a density of 1.28 and a flash point of 213.4±25.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 21339-55-9
Jingsj CID: J-1001719-9
Molecular Formula: C₁₂H₁₄N₂O₂
Chinese Name: 1-甲基-L-色氨酸
Molecular Weight: 218.252 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	223-226 ºC
Boiling Point	429.3±35.0 °C at 760 mmHg
Density	1.28
Flash Point	213.4±25.9 °C
Exact Mass	218.105530
PSA	68.25000
LogP	1.43
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.625

Activity & Biological Data

Target	Indoleamine 2,3-Dioxygenase (IDO)[1]
Additional Information	[1]. Huang GL, et, al. PEG-Poly(1-Methyl-l-Tryptophan)-Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2,3-Dioxygenase. Nanomaterials (Basel). 2019 May 9;9(5):719. [2]. Liu X, et, al. 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143(6):1516-1529.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 1-Methyl-L-tryptophan?

The CAS number of 1-Methyl-L-tryptophan is 21339-55-9.

What are the molecular formula and molecular weight of 1-Methyl-L-tryptophan?

1-Methyl-L-tryptophan has molecular formula C12H14N2O2 and molecular weight 218.252 g/mol.

What are the upstream and downstream products of 1-Methyl-L-tryptophan?

For 1-Methyl-L-tryptophan, Upstream Products: L-Tryptophan, iodomethane.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "1-Methyl-L-tryptophan (CAS 21339-55-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1001719-9 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.