Oxaprozin

奥沙普秦

Also known as: 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid, 4,5-Diphenyl-2-oxazolepropanoic acid, Daypro, Actirin, Durapro, Oxapro, Alvo, Oxaprozinum, Duraprost, 4,5-Diphenyl-2-oxazolepropionic Acid, 4,5-diphenyloxazole-2-propanoic acid

Oxaprozin (CAS 21256-18-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H15NO3 and a molecular weight of 293.317 g/mol. It is also known as 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid, 4,5-Diphenyl-2-oxazolepropanoic acid and Daypro. Key properties include a melting point of 154ºC, a boiling point of 467.0±33.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 236.2±25.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 21256-18-8
Jingsj CID: J-10645-6
Molecular Formula: C₁₈H₁₅NO₃
Chinese Name: 奥沙普秦
Molecular Weight: 293.317 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	154ºC
Boiling Point	467.0±33.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	236.2±25.4 °C
Exact Mass	293.105194
PSA	63.33000
LogP	4.19
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.595

Activity & Biological Data

Target	COX-1:2.2 μM (IC50) COX-2:36 μM (IC50) NF-κB
Additional Information	[1]. Ottonello L, et al. Delayed apoptosis of human monocytes exposed to immune complexes is reversed byoxaprozin: role of the Akt/IkappaB kinase/nuclear factor kappaB pathway. Br J Pharmacol. 2009 May;157(2):294-306. [2]. Montecucco F, et al. Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways. J Biomed Biotechnol. 2009;2009:478785.

Target

COX-1:2.2 μM (IC50) COX-2:36 μM (IC50) NF-κB

Additional Information

[1]. Ottonello L, et al. Delayed apoptosis of human monocytes exposed to immune complexes is reversed byoxaprozin: role of the Akt/IkappaB kinase/nuclear factor kappaB pathway. Br J Pharmacol. 2009 May;157(2):294-306. [2]. Montecucco F, et al. Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways. J Biomed Biotechnol. 2009;2009:478785.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Oxaprozin?

The CAS number of Oxaprozin is 21256-18-8.

What are the molecular formula and molecular weight of Oxaprozin?

Oxaprozin has molecular formula C18H15NO3 and molecular weight 293.317 g/mol.

What are the upstream and downstream products of Oxaprozin?

For Oxaprozin, Upstream Products: Succinic anhydride, Benzoin, 2-Phenylacetophenone.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Oxaprozin (CAS 21256-18-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-10645-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.