BMY 7378 dihydrochloride
8-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-8-氮杂螺[4.5]癸烷-7,9-二酮二盐酸盐
Also known as: BMY 7378 2hydrochloride, BMY 7378 dihydrochloride, BMY7378 HCl, 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, 8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, BMY 7378, MFCD00153771
BMY 7378 dihydrochloride (CAS 21102-95-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C22H33Cl2N3O3 and a molecular weight of 458.422 g/mol. It is also known as BMY 7378 2hydrochloride, BMY7378 HCl and 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride. Key properties include a melting point of 196.5-198.5 °C, a boiling point of 585.6ºC at 760 mmHg and a flash point of 307.9ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 21102-95-4
- Jingsj CID
- J-90083-0
- Molecular Formula
- C22H33Cl2N3O3
- Chinese Name
- 8-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-8-氮杂螺[4.5]癸烷-7,9-二酮二盐酸盐
- Molecular Weight
- 458.422 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 196.5-198.5 °C |
|---|---|
| Boiling Point | 585.6ºC at 760 mmHg |
| Flash Point | 307.9ºC |
| Exact Mass | 457.189911 |
| PSA | 53.09000 |
| LogP | 4.07140 |
| Appearance | solid | white |
| Vapor Pressure | 1.07E-13mmHg at 25°C |
| Additional Property | H2O: soluble |
Activity & Biological Data
| Target | rat α1A-adrenergic receptor:800 nM (Ki) hamster alpha1B-adrenergic receptor:600 nM (Ki) rat alpha1D-adrenergic receptor:2 nM (Ki) 5-HT1A Receptor |
|---|---|
| Additional Information | [1]. Piascik MT, et al. The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle. J Pharmacol Exp Ther. 1995;275(3):1583-1589. [2]. Goetz AS, et al. BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors. Eur J Pharmacol. 1995;272(2-3):R5-R6. |
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of BMY 7378 dihydrochloride?
The CAS number of BMY 7378 dihydrochloride is 21102-95-4.
What are the molecular formula and molecular weight of BMY 7378 dihydrochloride?
BMY 7378 dihydrochloride has molecular formula C22H33Cl2N3O3 and molecular weight 458.422 g/mol.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "BMY 7378 dihydrochloride (CAS 21102-95-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-90083-0 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.