Saikosaponin D

柴胡皂苷D

Also known as: (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside, Saikosaponian D, Saikosaponin D (8CI)

Saikosaponin D (CAS 20874-52-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C42H68O13 and a molecular weight of 780.982 g/mol. It is also known as (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside, Saikosaponian D and Saikosaponin D (8CI). Key properties include a melting point of 256- 259ºC, a boiling point of 893.7±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 494.3±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 20874-52-6
Jingsj CID: J-13257-8
Molecular Formula: C₄₂H₆₈O₁₃
Chinese Name: 柴胡皂苷D
Molecular Weight: 780.982 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	256- 259ºC
Boiling Point	893.7±65.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	494.3±34.3 °C
Exact Mass	780.466003
PSA	207.99000
LogP	3.65
Vapor Pressure	0.0±0.6 mmHg at 25°C
Refractive Index	1.617

Activity & Biological Data

Target	STAT3 NF-κB ERβ
Additional Information	[1]. Jang MJ, et al. Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion. Molecules. 2014 Dec 4;19(12):20340-9. [2]. Liu A, et al. Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. Chem Biol Interact. 2014 Nov 5;223:80-6. [3]. Que R, et al. Estrogen receptor-β-dependent effects of saikosaponin‑d on the suppression of oxidative stress-induced rat hepatic stellate cell activation. Int J Mol Med. 2018 Mar;41(3):1357-1364.

Target

STAT3 NF-κB ERβ

Additional Information

[1]. Jang MJ, et al. Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion. Molecules. 2014 Dec 4;19(12):20340-9. [2]. Liu A, et al. Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. Chem Biol Interact. 2014 Nov 5;223:80-6. [3]. Que R, et al. Estrogen receptor-β-dependent effects of saikosaponin‑d on the suppression of oxidative stress-induced rat hepatic stellate cell activation. Int J Mol Med. 2018 Mar;41(3):1357-1364.

Frequently Asked Questions

What is the CAS number of Saikosaponin D?

The CAS number of Saikosaponin D is 20874-52-6.

What are the molecular formula and molecular weight of Saikosaponin D?

Saikosaponin D has molecular formula C42H68O13 and molecular weight 780.982 g/mol.

What are the upstream and downstream products of Saikosaponin D?

For Saikosaponin D, Downstream Products: Saikosaponin B2.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Saikosaponin D (CAS 20874-52-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-13257-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.