2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine
N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍
Also known as: CHS-828, GMX1778, CHS 828, CHS828, GMX 1778, 1-(6-(4-Chlorophenoxy)hexyl)-3-cyano-2-(pyridin-4-yl)guanidine, N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine, Guanidine, N''-[6-(4-chlorophenoxy)hexyl]-N-cyano-N'-4-pyridinyl-, HS-828
2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine (CAS 200484-11-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C19H22ClN5O and a molecular weight of 371.864 g/mol. It is also known as CHS-828, GMX1778 and CHS 828. Key properties include a boiling point of 526.9±58.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 272.4±32.3 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 200484-11-3
- Jingsj CID
- J-1957030-5
- Molecular Formula
- C19H22ClN5O
- Chinese Name
- N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍
- Molecular Weight
- 371.864 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 526.9±58.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 272.4±32.3 °C |
| Exact Mass | 371.151276 |
| PSA | 82.33000 |
| LogP | 4.95 |
| Appearance | white solid |
| Vapor Pressure | 0.0±1.4 mmHg at 25°C |
| Refractive Index | 1.587 |
| Storage Conditions | -20℃ |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Watson M, et al. The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol. 2009 Nov;29(21):5872-88. [2]. Cerna D, et al. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid phosphoribosyltransferase1 (NAPRT1)-dependent manner. J Biol Chem. 2012 Jun 22;287(26):22408-17. |
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Frequently Asked Questions
What is the CAS number of 2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine?
The CAS number of 2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine is 200484-11-3.
What are the molecular formula and molecular weight of 2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine?
2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine has molecular formula C19H22ClN5O and molecular weight 371.864 g/mol.
Is 2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine hazardous?
2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine (CAS 200484-11-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957030-5 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.