Cucurbitacin E

葫芦素E

Also known as: α-Elaterin, alpha-Elaterin, A-Elaterin, Cucurbitacin E (SH)

Cucurbitacin E (CAS 18444-66-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C32H44O8 and a molecular weight of 556.687 g/mol. It is also known as α-Elaterin, alpha-Elaterin and A-Elaterin. Key properties include a melting point of 228-234ºC, a boiling point of 712.6±60.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 224.4±26.4 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
18444-66-1
Jingsj CID
J-1352635-5
Molecular Formula
C32H44O8
Chinese Name
葫芦素E
Molecular Weight
556.687 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point228-234ºC
Boiling Point712.6±60.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point224.4±26.4 °C
Exact Mass556.303589
PSA138.20000
LogP3.15
Vapor Pressure0.0±5.2 mmHg at 25°C
Refractive Index1.579

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

Targetcyclin B1/CDC2 Autophagy
Additional Information[1]. Hsu YC, et al. Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E. Cell Death Dis. 2014 Apr 24;5:e1198. [2]. Murtaza M, et al. Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway. PLoS One. 2017 Jun 9;12(6):e0178910.

Frequently Asked Questions

What is the CAS number of Cucurbitacin E?

The CAS number of Cucurbitacin E is 18444-66-1.

What are the molecular formula and molecular weight of Cucurbitacin E?

Cucurbitacin E has molecular formula C32H44O8 and molecular weight 556.687 g/mol.

Is Cucurbitacin E hazardous?

Cucurbitacin E has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Cucurbitacin E?

For Cucurbitacin E, Downstream Products: Cucurbitacin I.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Cucurbitacin E (CAS 18444-66-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1352635-5 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.