Alvimopan dihydrate

爱维莫潘二水合物

Also known as: Alvimopan dihydrate, Alvimopan hydrate, Entereg, ADL 8-2698, LY 246736, N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine dihydrate, 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid dihydrate

Alvimopan dihydrate (CAS 170098-38-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C25H36N2O6 and a molecular weight of 460.563 g/mol. It is also known as Alvimopan hydrate, Entereg and ADL 8-2698. Key properties include a melting point of 210-213ºC, a boiling point of 684.1ºC at 760mmHg, a density of 1.166g/cm3 and a flash point of 367.5ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 170098-38-1
Jingsj CID: J-1957879-6
Molecular Formula: C₂₅H₃₆N₂O₆
Chinese Name: 爱维莫潘二水合物
Molecular Weight: 460.563 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	210-213ºC
Boiling Point	684.1ºC at 760mmHg
Density	1.166g/cm3
Flash Point	367.5ºC
Exact Mass	460.257324
PSA	108.33000
LogP	3.25160
Vapor Pressure	1.18E-19mmHg at 25°C
Refractive Index	1.572
Storage Conditions	-20℃

Activity & Biological Data

Additional Information	[1]. NCBI BioAssay: 325959 [2]. Cassel JA, et al. [(3)H]Alvimopan binding to the micro opioid receptor: comparative binding kinetics of opioid antagonists. Eur J Pharmacol. 2005 Sep 27;520(1-3):29-36. [3]. Viscusi ER, et al. Alvimopan, a peripherally acting mu-opioid receptor antagonist, compared with placebo in postoperative ileus after major abdominal surgery: results of a randomized, double-blind, controlled study. Surg Endosc. 2006 Jan;20(1):64-70. [4]. Fukuda H, et al. The selective mu opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats. Brain Res. 2006 Aug 2;1102(1):63-70. [5]. Delaney CP, et al. Phase III trial of alvimopan, a novel, peripherally acting, mu opioid antagonist, for postoperative ileus after major abdominal surgery. Dis Colon Rectum. 2005 Jun;48(6):1114-25; discussion 1125-6; author reply 1127-9.

Additional Information

[1]. NCBI BioAssay: 325959 [2]. Cassel JA, et al. [(3)H]Alvimopan binding to the micro opioid receptor: comparative binding kinetics of opioid antagonists. Eur J Pharmacol. 2005 Sep 27;520(1-3):29-36. [3]. Viscusi ER, et al. Alvimopan, a peripherally acting mu-opioid receptor antagonist, compared with placebo in postoperative ileus after major abdominal surgery: results of a randomized, double-blind, controlled study. Surg Endosc. 2006 Jan;20(1):64-70. [4]. Fukuda H, et al. The selective mu opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats. Brain Res. 2006 Aug 2;1102(1):63-70. [5]. Delaney CP, et al. Phase III trial of alvimopan, a novel, peripherally acting, mu opioid antagonist, for postoperative ileus after major abdominal surgery. Dis Colon Rectum. 2005 Jun;48(6):1114-25; discussion 1125-6; author reply 1127-9.

Frequently Asked Questions

What is the CAS number of Alvimopan dihydrate?

The CAS number of Alvimopan dihydrate is 170098-38-1.

What are the molecular formula and molecular weight of Alvimopan dihydrate?

Alvimopan dihydrate has molecular formula C25H36N2O6 and molecular weight 460.563 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Alvimopan dihydrate (CAS 170098-38-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957879-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.