4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid

4-(2-羟乙基)-1-哌嗪丙磺酸

Also known as: HEPPS, EPPS, 3-[4-(2-Hydroxyethyl)-1-piperazine]propanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N-3-propanesulfonic acid, 4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid, N-(2-Hydroxyethyl)-N'-(3-sulfopropyl)piperazine

4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid (CAS 16052-06-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H20N2O4S and a molecular weight of 252.331 g/mol. It is also known as HEPPS, EPPS and 3-[4-(2-Hydroxyethyl)-1-piperazine]propanesulfonic acid. Key properties include a melting point of 237-239 °C(lit.) and a density of 1.3±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
16052-06-5
Jingsj CID
J-1101218-4
Molecular Formula
C9H20N2O4S
Chinese Name
4-(2-羟乙基)-1-哌嗪丙磺酸
Molecular Weight
252.331 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point237-239 °C(lit.)
Density1.3±0.1 g/cm3
Exact Mass252.114380
PSA89.46000
LogP-2.46
Refractive Index1.537
Storage ConditionsStore at RT.
Additional PropertyH2O: 1 M at 20 °C, clear, colorless

Activity & Biological Data

Additional Information[1]. Kim HY, et al. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nat Commun. 2015 Dec 8;6:8997.

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid?

The CAS number of 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid is 16052-06-5.

What are the molecular formula and molecular weight of 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid?

4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid has molecular formula C9H20N2O4S and molecular weight 252.331 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid (CAS 16052-06-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1101218-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.