Pizotifen

Also known as: 4-(1-Methyl-4-piperidylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene, 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine, 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine, BC 105, Pizotifenum, Pizotylene, Pizotyline, Sandomigran, UNII:0BY8440V3N

Pizotifen (CAS 15574-96-6) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C19H21NS and a molecular weight of 295.442 g/mol. Key properties include a melting point of 140-142°C, a boiling point of 436.7±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 217.9±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H361 — Suspected of damaging fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 15574-96-6
Jingsj CID: J-15785-6
Molecular Formula: C₁₉H₂₁NS
Molecular Weight: 295.442 g/mol
Category: Aromatic Hydrocarbons
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	140-142°C
Boiling Point	436.7±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	217.9±28.7 °C
Exact Mass	295.139465
PSA	31.48000
LogP	6.13
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.631
Storage Conditions	Refrigerator

GHS Safety & Compliance

Irritant / Health HazardSignal word: Warning

H302 — Harmful if swallowed
H361 — Suspected of damaging fertility or the unborn child

Activity & Biological Data

Target	5-HT2A Receptor 5-HT1C Receptor
Additional Information	[1]. Mylecharane EJ, et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52. [2]. Lin OA, et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026. [3]. Ujházy E, et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8.

Target

5-HT2A Receptor 5-HT1C Receptor

Additional Information

[1]. Mylecharane EJ, et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52. [2]. Lin OA, et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026. [3]. Ujházy E, et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8.

Frequently Asked Questions

What is the CAS number of Pizotifen?

The CAS number of Pizotifen is 15574-96-6.

What are the molecular formula and molecular weight of Pizotifen?

Pizotifen has molecular formula C19H21NS and molecular weight 295.442 g/mol.

Is Pizotifen hazardous?

Pizotifen has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H361 — Suspected of damaging fertility or the unborn child.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Pizotifen (CAS 15574-96-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15785-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.