4-Hydroxy-6-(trifluoromethyl)pyrimidine
4-羟基-6-(三氟甲基)嘧啶
Also known as: 6-(trifluoromethyl)pyrimidin-4-ol, 6-Trifluoromethyl-4(1H)-pyrimidinone, 6-Trifluoromethyl-4-pyrimidinol, 4-Pyrimidinol, 6-(trifluoromethyl)-, MFCD00192530
4-Hydroxy-6-(trifluoromethyl)pyrimidine (CAS 1546-78-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C5H3F3N2O and a molecular weight of 164.085 g/mol. It is also known as 6-(trifluoromethyl)pyrimidin-4-ol, 6-Trifluoromethyl-4(1H)-pyrimidinone and 6-Trifluoromethyl-4-pyrimidinol. Key properties include a melting point of 169-171 °C(lit.), a boiling point of 229.0±35.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 92.3±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1546-78-7
- Jingsj CID
- J-15501-2
- Molecular Formula
- C5H3F3N2O
- Chinese Name
- 4-羟基-6-(三氟甲基)嘧啶
- Molecular Weight
- 164.085 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 169-171 °C(lit.) |
|---|---|
| Boiling Point | 229.0±35.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 92.3±25.9 °C |
| Exact Mass | 164.019745 |
| PSA | 46.01000 |
| LogP | 0.74 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.456 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 4-Hydroxy-6-(trifluoromethyl)pyrimidine?
The CAS number of 4-Hydroxy-6-(trifluoromethyl)pyrimidine is 1546-78-7.
What are the molecular formula and molecular weight of 4-Hydroxy-6-(trifluoromethyl)pyrimidine?
4-Hydroxy-6-(trifluoromethyl)pyrimidine has molecular formula C5H3F3N2O and molecular weight 164.085 g/mol.
Is 4-Hydroxy-6-(trifluoromethyl)pyrimidine hazardous?
4-Hydroxy-6-(trifluoromethyl)pyrimidine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 4-Hydroxy-6-(trifluoromethyl)pyrimidine?
For 4-Hydroxy-6-(trifluoromethyl)pyrimidine, Upstream Products: 4-Hydroxy-6-(trifluoromethyl)pyrimidine-2-thiol; Downstream Products: 4-Chloro-6-(trifluoromethyl)pyrimidine, 6-(Trifluoromethyl)pyrimidin-4-amine, 4-(Trifluoromethyl)pyrimidine-5-carboxylic acid.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "4-Hydroxy-6-(trifluoromethyl)pyrimidine (CAS 1546-78-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15501-2 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.