Oxymetazoline

羟甲唑啉

Also known as: 2-(4-t-butyl-2,6-dimethyl-3-hydroxy-benzyl)-2-imidazoline, 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-6-tert-butylphenol, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol, Hazol, Iliadin, Nafrine, Nezeril, Oximetazolinum, Oxylazine, Oxymethazoline, Rhinofrenol, Sinerol, Afrin, Nasivin, Navisin, H-990, Rhinolitan

Oxymetazoline (CAS 1491-59-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H24N2O and a molecular weight of 260.37500 g/mol. It is also known as 2-(4-t-butyl-2,6-dimethyl-3-hydroxy-benzyl)-2-imidazoline, 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-6-tert-butylphenol and 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol. Key properties include a melting point of 182ºC, a boiling point of 431.9ºC at 760 mmHg, a density of 1.08 g/cm3 and a flash point of 215ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1491-59-4
Jingsj CID: J-1984155-3
Molecular Formula: C₁₆H₂₄N₂O
Chinese Name: 羟甲唑啉
Molecular Weight: 260.37500 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	182ºC
Boiling Point	431.9ºC at 760 mmHg
Density	1.08 g/cm3
Flash Point	215ºC
Exact Mass	260.18900
PSA	44.62000
LogP	2.61510
Vapor Pressure	4.59E-08mmHg at 25°C

Activity & Biological Data

Target	IC50: 0.02 μM (α1A), 0.25 μM (α1B), 0.58 μM (α2A), 0.13 μM (α2C)[1]
Additional Information	[1]. Haenisch B, et al. Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundam Clin Pharmacol. 2010 Dec;24(6):729-39.

Customs & Trade Information

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Oxymetazoline?

The CAS number of Oxymetazoline is 1491-59-4.

What are the molecular formula and molecular weight of Oxymetazoline?

Oxymetazoline has molecular formula C16H24N2O and molecular weight 260.37500 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Oxymetazoline (CAS 1491-59-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1984155-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.