5β-Dihydrocortisol

5β-二氢皮质醇

Also known as: 11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione, 5β-Pregnane-11β,17α,21-triol-3,20-dione, Dihydrocortisol, NSC 15473

5β-Dihydrocortisol (CAS 1482-50-4) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C21H32O5 and a molecular weight of 364.47600 g/mol. It is also known as 11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione, 5β-Pregnane-11β,17α,21-triol-3,20-dione and Dihydrocortisol. Key properties include a boiling point of 544.5ºC at 760mmHg, a density of 1.249g/cm3 and a flash point of 297.1ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1482-50-4
Jingsj CID: J-1180389-0
Molecular Formula: C₂₁H₃₂O₅
Chinese Name: 5β-二氢皮质醇
Molecular Weight: 364.47600 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	544.5ºC at 760mmHg
Density	1.249g/cm3
Flash Point	297.1ºC
Exact Mass	364.22500
PSA	94.83000
LogP	1.86150
Refractive Index	1.569

Activity & Biological Data

Additional Information	[1]. Marver D, et, al. Dihydrocortisol: a potential mineralocorticoid. J Steroid Biochem. 1978 Jan;9(1):1-7. [2]. Kallubai M, et, al. Spectroscopic evaluation of synthesized 5β-dihydrocortisol and 5β-dihydrocortisol acetate binding mechanism with human serum albumin and their role in anticancer activity. J Biomol Struct Dyn. 2019 Feb;37(3):623-640. [3]. Southren AL, et, al. 5 beta-Dihydrocortisol: possible mediator of the ocular hypertension in glaucoma. Invest Ophthalmol Vis Sci. 1985 Mar;26(3):393-5. [4]. Appanna N, et, al. Differential activity and expression of human 5β-reductase (AKR1D1) splice variants. J Mol Endocrinol. 2021 Mar;66(3):181-194. [5]. Weinstein BI, et, al. Potentiation of glucocorticoid activity by 5 beta-dihydrocortisol: its role in glaucoma. Science. 1983 Oct 14;222(4620):172-3.

Additional Information

[1]. Marver D, et, al. Dihydrocortisol: a potential mineralocorticoid. J Steroid Biochem. 1978 Jan;9(1):1-7. [2]. Kallubai M, et, al. Spectroscopic evaluation of synthesized 5β-dihydrocortisol and 5β-dihydrocortisol acetate binding mechanism with human serum albumin and their role in anticancer activity. J Biomol Struct Dyn. 2019 Feb;37(3):623-640. [3]. Southren AL, et, al. 5 beta-Dihydrocortisol: possible mediator of the ocular hypertension in glaucoma. Invest Ophthalmol Vis Sci. 1985 Mar;26(3):393-5. [4]. Appanna N, et, al. Differential activity and expression of human 5β-reductase (AKR1D1) splice variants. J Mol Endocrinol. 2021 Mar;66(3):181-194. [5]. Weinstein BI, et, al. Potentiation of glucocorticoid activity by 5 beta-dihydrocortisol: its role in glaucoma. Science. 1983 Oct 14;222(4620):172-3.

Frequently Asked Questions

What is the CAS number of 5β-Dihydrocortisol?

The CAS number of 5β-Dihydrocortisol is 1482-50-4.

What are the molecular formula and molecular weight of 5β-Dihydrocortisol?

5β-Dihydrocortisol has molecular formula C21H32O5 and molecular weight 364.47600 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5β-Dihydrocortisol (CAS 1482-50-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1180389-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.