Sulfamethizole

Also known as: 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide, 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzene-1-sulfonamide, N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide, Sulphamethizole, Sulfamethylthiadiazole, 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole, 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole, Lucosil, Methazol, Thiosulfil, Urolucosil

Sulfamethizole (CAS 144-82-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C9H10N4O2S2 and a molecular weight of 270.331 g/mol. Key properties include a melting point of 210 °C, a boiling point of 504.9±52.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 259.1±30.7 °C. It is classified under GHS with signal word Warning and hazard statements H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 144-82-1
Jingsj CID: J-25422-5
Molecular Formula: C₉H₁₀N₄O₂S₂
Molecular Weight: 270.331 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	210 °C
Boiling Point	504.9±52.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	259.1±30.7 °C
Exact Mass	270.024506
PSA	134.59000
LogP	0.51
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.687

GHS Safety & Compliance

IrritantSignal word: Warning

H317 — May cause an allergic skin reaction

Activity & Biological Data

Additional Information	[1]. Watanabe, H. and J.W. Hastings, Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta, 1990. 1017(3): p. 229-34. [2]. Kerrn, M.B., N. Frimodt-Moller, and F. Espersen, Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model. Antimicrob Agents Chemother, 2003. 47(3): p. 1002-9.

Additional Information

[1]. Watanabe, H. and J.W. Hastings, Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta, 1990. 1017(3): p. 229-34. [2]. Kerrn, M.B., N. Frimodt-Moller, and F. Espersen, Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model. Antimicrob Agents Chemother, 2003. 47(3): p. 1002-9.

Customs & Trade Information

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Sulfamethizole?

The CAS number of Sulfamethizole is 144-82-1.

What are the molecular formula and molecular weight of Sulfamethizole?

Sulfamethizole has molecular formula C9H10N4O2S2 and molecular weight 270.331 g/mol.

Is Sulfamethizole hazardous?

Sulfamethizole has GHS signal word Warning and hazard statements H317 — May cause an allergic skin reaction.

What are the upstream and downstream products of Sulfamethizole?

For Sulfamethizole, Upstream Products: N-Acetylsulfanilyl chloride, 4-Nitrobenzenesulfonyl chloride, 2-Amino-5-methyl-1,3,4-thiadiazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Sulfamethizole (CAS 144-82-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25422-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.