Vinblastine sulfate

硫酸长春碱

Also known as: Vinblastine sulfate, Vincaleukoblastine sulfate, VLB, Velban, Velbe, NSC-49842, 29060-LE, Periblastine, Velsar, Exal, Rozevinsulfate

Vinblastine sulfate (CAS 143-67-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C46H60N4O13S and a molecular weight of 909.053 g/mol. It is also known as Vincaleukoblastine sulfate, VLB and Velban. Key properties include a melting point of 267 °C (dec.)(lit.) and a density of 1.37 g/cm3. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
143-67-9
Jingsj CID
J-14670-8
Molecular Formula
C46H60N4O13S
Chinese Name
硫酸长春碱
Molecular Weight
909.053 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point267 °C (dec.)(lit.)
Density1.37 g/cm3
Exact Mass908.387756
PSA237.08000
LogP4.35970
Additional Property>=1 g/100 mL at 24.5 ºC

GHS Safety & Compliance

Corrosion / IrritantSignal word: Danger
  • H302 — Harmful if swallowed
  • H315 — Causes skin irritation
  • H318 — Causes serious eye damage
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetIC50: 8.9 μM(nAChR)[1]
Additional Information[1]. McKay DB, et al. Nicotinic and nonnicotinic receptor-mediated actions of vinblastine. Proc Soc Exp Biol Med. 1993 Jul;203(3):372-6. [2]. Pandya P, et al. Molecular recognition pattern of cytotoxic alkaloid vinblastine with multiple targets. J Mol Graph Model. 2014 Nov;54:1-9. [3]. Calviño E, et al. JNK and NFκB dependence of apoptosis induced by vinblastine in human acute promyelocytic leukaemia cells. Cell Biochem Funct. 2015 Jun;33(4):211-9. [4]. Selimovic D, et al. Vinblastine-induced apoptosis of melanoma cells is mediated by Ras homologous A protein (Rho A) via mitochondrial and non-mitochondrial-dependent mechanisms. Apoptosis. 2013 Aug;18(8):980-97. [5]. Bánóczi Z, et al. Synthesis and in vitro antitumor effect of vinblastine derivative-oligoarginine conjugates. Bioconjug Chem. 2010 Nov 17;21(11):1948-55.

Customs & Trade Information

HS Code2942000000

Frequently Asked Questions

What is the CAS number of Vinblastine sulfate?

The CAS number of Vinblastine sulfate is 143-67-9.

What are the molecular formula and molecular weight of Vinblastine sulfate?

Vinblastine sulfate has molecular formula C46H60N4O13S and molecular weight 909.053 g/mol.

Is Vinblastine sulfate hazardous?

Vinblastine sulfate has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H318 — Causes serious eye damage.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Vinblastine sulfate (CAS 143-67-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-14670-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.