Acetazolamide sodium

乙酰唑胺钠

Also known as: Acetazolamide sodium salt, Sodium acetazolamide, Diamox Parenteral, Vetamox, UNII-429ZT169UH, N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide monosodium salt, Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-, monosodium salt

Acetazolamide sodium (CAS 1424-27-7) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C4H5N4NaO3S2 and a molecular weight of 244.22700 g/mol. It is also known as Acetazolamide sodium salt, Sodium acetazolamide and Diamox Parenteral. Key property: a melting point of 258-259ºC (EFFERVESCENCE). No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1424-27-7
Jingsj CID: J-1955114-6
Molecular Formula: C₄H₅N₄NaO₃S₂
Chinese Name: 乙酰唑胺钠
Molecular Weight: 244.22700 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	258-259ºC (EFFERVESCENCE)
Exact Mass	243.97000
PSA	142.87000
LogP	0.78380

Activity & Biological Data

Additional Information	[1]. Bayat Mokhtari R, et al. Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 Feb 24;17(1):156. [2]. Hou Z, et al. Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site. Eur J Med Chem. 2017 May 26;132:1-10. [3]. Gao H, et al. Combined treatment with acetazolamide and cisplatin enhances chemosensitivity in laryngeal carcinoma Hep-2 cells. Oncol Lett. 2018 Jun;15(6):9299-9306. [4]. Kassamali R, et al. Acetazolamide: a forgotten diuretic agent. Cardiol Rev. 2011 Nov-Dec;19(6):276-8. [5]. Jabeen E, et al. Interaction of antihypertensive acetazolamide with nonsteroidal anti-inflammatory drugs. J Photochem Photobiol B. 2013 Aug 5;125:155-63. [6]. Abutaleb NS, et al. In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection. Microb Pathog. 2022 Mar;164:105454.

Additional Information

[1]. Bayat Mokhtari R, et al. Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 Feb 24;17(1):156. [2]. Hou Z, et al. Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site. Eur J Med Chem. 2017 May 26;132:1-10. [3]. Gao H, et al. Combined treatment with acetazolamide and cisplatin enhances chemosensitivity in laryngeal carcinoma Hep-2 cells. Oncol Lett. 2018 Jun;15(6):9299-9306. [4]. Kassamali R, et al. Acetazolamide: a forgotten diuretic agent. Cardiol Rev. 2011 Nov-Dec;19(6):276-8. [5]. Jabeen E, et al. Interaction of antihypertensive acetazolamide with nonsteroidal anti-inflammatory drugs. J Photochem Photobiol B. 2013 Aug 5;125:155-63. [6]. Abutaleb NS, et al. In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection. Microb Pathog. 2022 Mar;164:105454.

Frequently Asked Questions

What is the CAS number of Acetazolamide sodium?

The CAS number of Acetazolamide sodium is 1424-27-7.

What are the molecular formula and molecular weight of Acetazolamide sodium?

Acetazolamide sodium has molecular formula C4H5N4NaO3S2 and molecular weight 244.22700 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Acetazolamide sodium (CAS 1424-27-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955114-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.