Entecavir

恩替卡韦

Also known as: Baraclude, ETV, BMS-200475-01, SQ 34676, 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one, 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one, 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-9H-purin-6-ol, 9-(4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine, entecavir (anhydrous), UNII-NNU2O4609D

Entecavir (CAS 142217-69-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H15N5O3 and a molecular weight of 277.279 g/mol. It is also known as Baraclude, ETV and BMS-200475-01. Key properties include a melting point of 249-252ºC, a boiling point of 734.2ºC at 760 mmHg, a density of 1.8±0.1 g/cm3 and a flash point of 397.9ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 142217-69-4
Jingsj CID: J-1956193-4
Molecular Formula: C₁₂H₁₅N₅O₃
Chinese Name: 恩替卡韦
Molecular Weight: 277.279 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	249-252ºC
Boiling Point	734.2ºC at 760 mmHg
Density	1.8±0.1 g/cm3
Flash Point	397.9ºC
Exact Mass	277.117493
PSA	130.05000
LogP	-0.96
Refractive Index	1.837
Storage Conditions	-20°C Freezer

Activity & Biological Data

Target	EC50: 3.75 nM (anti-HBV, HepG2 cell)[2]
Additional Information	[1]. Innaimo SF, et al. Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus. Antimicrob Agents Chemother. 1997 Jul;41(7):1444-9. [2]. Rivkin A, et al. A review of entecavir in the treatment of chronic hepatitis B infection. Curr Med Res Opin. 2005 Nov;21(11):1845-57. [3]. Genovesi EV, et al. Efficacy of the carbocyclic 2'-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection. Antimicrob Agents Chemother. 1998 Dec;42(12):3209-18.

Target

EC50: 3.75 nM (anti-HBV, HepG2 cell)[2]

Additional Information

[1]. Innaimo SF, et al. Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus. Antimicrob Agents Chemother. 1997 Jul;41(7):1444-9. [2]. Rivkin A, et al. A review of entecavir in the treatment of chronic hepatitis B infection. Curr Med Res Opin. 2005 Nov;21(11):1845-57. [3]. Genovesi EV, et al. Efficacy of the carbocyclic 2'-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection. Antimicrob Agents Chemother. 1998 Dec;42(12):3209-18.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Entecavir?

The CAS number of Entecavir is 142217-69-4.

What are the molecular formula and molecular weight of Entecavir?

Entecavir has molecular formula C12H15N5O3 and molecular weight 277.279 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Entecavir (CAS 142217-69-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956193-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.