Sarpogrelate hydrochloride

盐酸沙格雷酯

Also known as: 4-((1-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobutanoic acid hydrochloride, 4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic acid, hydrochloride, 4-{[1-(Dimethylamino)-3-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}-2-propanyl]oxy}-4-oxobutanoic acid hydrochloride (1:1), 4-{[1-(Dimethylamino)-3-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}propan-2-yl]oxy}-4-oxobutanoic acid hydrochloride (1:1), ANPLAG, Anplag, Butanedioic acid, mono(2-(dimethylamino)-1-((2-(2-(3-methoxyphenyl)ethyl)phenoxy)methyl)ethyl) ester, hydrochloride, Butanedioic acid, mono[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester, hydrochloride (1:1), Butanedioic acid, mono[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester, hydrochloride (9CI), Butanedioic acid, mono[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester, hydrochloride, (+-)-, MCI 9042, MCI-9042, MCI9042, Sarpogrelate (hydrochloride), Sarpogrelate HCl, Sarpogrelate Hydrochloride (mixture of isomers), Sarpogrelate hydrochloride, UNII:FQN8N8QP1B

Sarpogrelate hydrochloride (CAS 135159-51-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C24H32ClNO6 and a molecular weight of 465.967 g/mol. It is also known as 4-((1-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobutanoic acid hydrochloride, 4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic acid, hydrochloride and 4-{[1-(Dimethylamino)-3-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}-2-propanyl]oxy}-4-oxobutanoic acid hydrochloride (1:1). Key properties include a melting point of 145-148°C, a boiling point of 585.9ºC at 760 mmHg and a flash point of 308.1ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 135159-51-2
Jingsj CID: J-1975807-7
Molecular Formula: C₂₄H₃₂ClNO₆
Chinese Name: 盐酸沙格雷酯
Molecular Weight: 465.967 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	145-148°C
Boiling Point	585.9ºC at 760 mmHg
Flash Point	308.1ºC
Exact Mass	465.191803
PSA	85.30000
LogP	3.99940
Vapor Pressure	1.43E-14mmHg at 25°C
Storage Conditions	Desiccate at RT

GHS Safety & Compliance

Irritant / Environmental HazardSignal word: Warning

H302 — Harmful if swallowed
H400 — Very toxic to aquatic life

Activity & Biological Data

Additional Information	[1]. Nishio, H., A. Inoue, and Y. Nakata, Binding affinity of sarpogrelate, a new antiplatelet agent, and its metabolite for serotonin receptor subtypes. Arch Int Pharmacodyn Ther, 1996. 331(2): p. 189-202. [2]. Pertz, H. and S. Elz, In-vitro pharmacology of sarpogrelate and the enantiomers of its major metabolite: 5-HT2A receptor specificity, stereoselectivity and modulation of ritanserin-induced depression of 5-HT contractions in rat tail artery. J Pharm Pharma [3]. Miyazaki, M., et al., Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease. J Cardiovasc Pharmacol, 2007. 49(4): p. 221-7.

Additional Information

[1]. Nishio, H., A. Inoue, and Y. Nakata, Binding affinity of sarpogrelate, a new antiplatelet agent, and its metabolite for serotonin receptor subtypes. Arch Int Pharmacodyn Ther, 1996. 331(2): p. 189-202. [2]. Pertz, H. and S. Elz, In-vitro pharmacology of sarpogrelate and the enantiomers of its major metabolite: 5-HT2A receptor specificity, stereoselectivity and modulation of ritanserin-induced depression of 5-HT contractions in rat tail artery. J Pharm Pharma [3]. Miyazaki, M., et al., Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease. J Cardiovasc Pharmacol, 2007. 49(4): p. 221-7.

Frequently Asked Questions

What is the CAS number of Sarpogrelate hydrochloride?

The CAS number of Sarpogrelate hydrochloride is 135159-51-2.

What are the molecular formula and molecular weight of Sarpogrelate hydrochloride?

Sarpogrelate hydrochloride has molecular formula C24H32ClNO6 and molecular weight 465.967 g/mol.

Is Sarpogrelate hydrochloride hazardous?

Sarpogrelate hydrochloride has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H400 — Very toxic to aquatic life.

What are the upstream and downstream products of Sarpogrelate hydrochloride?

For Sarpogrelate hydrochloride, Upstream Products: Succinic anhydride, 1-(Dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-2-propanol hydrochloride; Downstream Products: Succinic acid.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Sarpogrelate hydrochloride (CAS 135159-51-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975807-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.