N-Ethylmaleimide
Also known as: 1-ethyl-1H-pyrrole-2,5-dione, Ethylmaleimide, NEM, 1-ethylmaleimide, N-ethylmaleic imide
N-Ethylmaleimide (CAS 128-53-0) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C6H7NO2 and a molecular weight of 125.13 g/mol. Key properties include a melting point of 43-46 °C(lit.), a boiling point of 210.0±9.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 73.3±0.0 °C. It is classified under GHS with signal word Danger and hazard statements H300, H311 — Toxic in contact with skin and H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 128-53-0
- Jingsj CID
- J-32643-8
- Molecular Formula
- C6H7NO2
- Molecular Weight
- 125.13 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 43-46 °C(lit.) |
|---|---|
| Boiling Point | 210.0±9.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 73.3±0.0 °C |
| Exact Mass | 125.047676 |
| PSA | 37.38000 |
| LogP | 0.68 |
| Vapor Pressure | 0.2±0.4 mmHg at 25°C |
| Refractive Index | 1.514 |
| Storage Conditions | 2-8°C |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate. |
| Additional Property | 1 g/L (20 ºC) |
GHS Safety & Compliance
- H300
- H311 — Toxic in contact with skin
- H314 — Causes severe skin burns and eye damage
- H317 — May cause an allergic skin reaction
Activity & Biological Data
| Target | Cysteine protease[1] |
|---|---|
| Additional Information | [1]. Wu KH, et al. Cys32 and His105 are the critical residues for the calcium-dependent cysteine proteolyticactivity of CvaB, an ATP-binding cassette transporter. J Biol Chem. 2004 Jan 9;279(2):901-9. [2]. Hatase O , et al. Specific inhibition of phosphate transport in mitochondria by N-ethylmaleimide. Journal of Bioenergetics, 1973, 5(1):1-15. |
Customs & Trade Information
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of N-Ethylmaleimide?
The CAS number of N-Ethylmaleimide is 128-53-0.
What are the molecular formula and molecular weight of N-Ethylmaleimide?
N-Ethylmaleimide has molecular formula C6H7NO2 and molecular weight 125.13 g/mol.
Is N-Ethylmaleimide hazardous?
N-Ethylmaleimide has GHS signal word Danger and hazard statements H300; H311 — Toxic in contact with skin; H314 — Causes severe skin burns and eye damage.
What are the upstream and downstream products of N-Ethylmaleimide?
For N-Ethylmaleimide, Upstream Products: Maleic anhydride, Ethylamine hydrochloride, N-Ethylmaleamic acid; Downstream Products: N-Ethylmaleamic acid, N-Ethylsuccinimide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "N-Ethylmaleimide (CAS 128-53-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-32643-8 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.