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Sulfisoxazole

Also known as: Sulfafurazole, Gantrizin, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, 4-Amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide, 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisooxazole, N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, Sulfasoxazole, MFCD00003150, EINECS 204-858-9

Sulfisoxazole (CAS 127-69-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C11H13N3O3S and a molecular weight of 267.304 g/mol. Key properties include a melting point of 195°C, a boiling point of 482.2±55.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 245.4±31.5 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
127-69-5
Jingsj CID
J-33531-5
Molecular Formula
C11H13N3O3S
Molecular Weight
267.304 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point195°C
Boiling Point482.2±55.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point245.4±31.5 °C
Exact Mass267.067749
PSA106.60000
LogP1.01
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.626
Storage Conditions2-8°C
StabilityStable. Incompatible with strong oxidizing agents.
Additional Property<0.1 g/100 mL at 22.5 ºC

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Chan, M.F., et al., Identification of a new class of ETA selective endothelin antagonists by pharmacophore directed screening. Biochem Biophys Res Commun, 1994. 201(1): p. 228-34. [2]. http://www.mayoclinic.org/drugs-supplements/sulfisoxazole-oral-route/description/drg-20072998

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Sulfisoxazole?

The CAS number of Sulfisoxazole is 127-69-5.

What are the molecular formula and molecular weight of Sulfisoxazole?

Sulfisoxazole has molecular formula C11H13N3O3S and molecular weight 267.304 g/mol.

Is Sulfisoxazole hazardous?

Sulfisoxazole has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Sulfisoxazole?

For Sulfisoxazole, Upstream Products: N-(3,4-dimethyl-5-isoxazolyl)-4-nitrobenzenesulfonamide, 3,4-Dimethylisoxazol-5-amine, 4-Nitrobenzenesulfonyl chloride; Downstream Products: Sulfisoxazole Acetyl, 3,4-Dimethylisoxazol-5-amine, 3,4-Dimethylisoxazol-5-ol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Sulfisoxazole (CAS 127-69-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33531-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.