Azelnidipine
阿折地平
Also known as: CS-905, RS-9054, 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 3-(1-(Diphenylmethyl)-3-azetidinyl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, 3-[1-(Diphenylmethyl)azetidin-3-yl] 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, CALBLOCK, Azelnidipine (Calblock), MFCD00865803, UNII:PV23P19YUG
Azelnidipine (CAS 123524-52-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C33H34N4O6 and a molecular weight of 582.646 g/mol. It is also known as CS-905, RS-9054 and 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Key properties include a melting point of 120-126ºC, a boiling point of 709.3±60.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 382.8±32.9 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 123524-52-7
- Jingsj CID
- J-1961722-8
- Molecular Formula
- C33H34N4O6
- Chinese Name
- 阿折地平
- Molecular Weight
- 582.646 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 120-126ºC |
|---|---|
| Boiling Point | 709.3±60.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 382.8±32.9 °C |
| Exact Mass | 582.247864 |
| PSA | 139.71000 |
| LogP | 4.21 |
| Vapor Pressure | 0.0±2.3 mmHg at 25°C |
| Refractive Index | 1.659 |
| Storage Conditions | Room temp |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H318 — Causes serious eye damage
Activity & Biological Data
| Additional Information | [1]. Komoda H, Inoue T, Node K. Anti-inflammatory properties of azelnidipine, a dihydropyridine-based calcium channel blocker. Clin Exp Hypertens. 2010 Jan;32(2):121-8. [2]. Kain V, Kumar S, Sitasawad SL. Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis. Cardiovasc Diabetol. 2011 Nov 4;10:97. [3]. Takano Y, Ueyama T, Ishikura F. Azelnidipine, unique calcium channel blocker could prevent stress-induced cardiac dysfunction like α·β blocker. J Cardiol. 2012 Jul;60(1):18-22. [4]. Shimizu T, Tanaka T, Iso T et al. Azelnidipine inhibits MSX2-dependent osteogenic differentiation and matrix mineralization of vascular smooth muscle cells. Int Heart J. 2012;53(5):331-5. [5]. Ohyama T, Sato K, Kishimoto K et al. Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence. Br J Pharmacol. 2012 Feb;165(4b):1173-87. |
|---|
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Azelnidipine?
The CAS number of Azelnidipine is 123524-52-7.
What are the molecular formula and molecular weight of Azelnidipine?
Azelnidipine has molecular formula C33H34N4O6 and molecular weight 582.646 g/mol.
Is Azelnidipine hazardous?
Azelnidipine has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H318 — Causes serious eye damage.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Azelnidipine (CAS 123524-52-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961722-8 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.