Methylene Blue hydrate

亚甲基蓝水合物

Also known as: Methylene Blue hydrate, Methylthioninium chloride hydrate, Basic Blue 9 hydrate, CI 52015 hydrate, 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride hydrate, Methylene Blue trihydrate, Methylene Blue for microscopy, Methylene Blue redox indicator, MFCD00150006

Methylene Blue hydrate (CAS 122965-43-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H20ClN3OS and a molecular weight of 337.86800 g/mol. It is also known as Methylthioninium chloride hydrate, Basic Blue 9 hydrate and CI 52015 hydrate. Key properties include a melting point of 190ºC and a density of 0.6600g/ml. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 122965-43-9
Jingsj CID: J-1116046-9
Molecular Formula: C₁₆H₂₀ClN₃OS
Chinese Name: 亚甲基蓝水合物
Molecular Weight: 337.86800 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	190ºC
Density	0.6600g/ml
Exact Mass	337.10200
PSA	56.61000
Appearance	Fine Crystalline Powder \| Green
Additional Property	H2O: soluble4mg/4ml \| Soluble in water, alcohol, acetic acid, glycerol and chloroform. Insoluble in ether.

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Additional Information	[1]. Klamer D, et, al. Phencyclidine-induced behaviour in mice prevented by methylene blue. Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):65-72. [2]. Hochgräfe K, et, al. Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau. Acta Neuropathol Commun. 2015 May 10;3:25. [3]. Fenn AM, et, al. Methylene blue attenuates traumatic brain injury-associated neuroinflammation and acute depressive-like behavior in mice. J Neurotrauma. 2015 Jan 15;32(2):127-38.

Additional Information

[1]. Klamer D, et, al. Phencyclidine-induced behaviour in mice prevented by methylene blue. Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):65-72. [2]. Hochgräfe K, et, al. Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau. Acta Neuropathol Commun. 2015 May 10;3:25. [3]. Fenn AM, et, al. Methylene blue attenuates traumatic brain injury-associated neuroinflammation and acute depressive-like behavior in mice. J Neurotrauma. 2015 Jan 15;32(2):127-38.

Frequently Asked Questions

What is the CAS number of Methylene Blue hydrate?

The CAS number of Methylene Blue hydrate is 122965-43-9.

What are the molecular formula and molecular weight of Methylene Blue hydrate?

Methylene Blue hydrate has molecular formula C16H20ClN3OS and molecular weight 337.86800 g/mol.

Is Methylene Blue hydrate hazardous?

Methylene Blue hydrate has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Methylene Blue hydrate (CAS 122965-43-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1116046-9 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.