Grepafloxacin

格帕沙星

Also known as: 1-Cyclopropyl-6-fluoro-7-(3-methyl-1-piperazinyl)-5-methyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-5-methyl-6-fluoro-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, GREPAFLOXACIN, Grepafloxacin USP/EP/BP, OPC-17116, dl-Grepafloxacin, MFCD00865116

Grepafloxacin (CAS 119914-60-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H22FN3O3 and a molecular weight of 359.39500 g/mol. It is also known as 1-Cyclopropyl-6-fluoro-7-(3-methyl-1-piperazinyl)-5-methyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-5-methyl-6-fluoro-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid. Key properties include a melting point of 189-192ºC, a boiling point of 610ºC at 760mmHg, a density of 1.366 and a flash point of 322.7ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 119914-60-2
Jingsj CID: J-1958905-7
Molecular Formula: C₁₉H₂₂FN₃O₃
Chinese Name: 格帕沙星
Molecular Weight: 359.39500 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	189-192ºC
Boiling Point	610ºC at 760mmHg
Density	1.366
Flash Point	322.7ºC
Exact Mass	359.16500
PSA	74.57000
LogP	2.67400

Activity & Biological Data

Additional Information	[1]. Efthymiopoulos C. Pharmacokinetics of grepafloxacin. J Antimicrob Chemother. 1997;40 Suppl A:35-43. [2]. Owen K. Comparative grepafloxacin phototoxicity in mouse skin. J Antimicrob Chemother. 1998;42(2):261-264. [3]. Cynamon MH, et al. The activity of grepafloxacin in two murine models of Mycobacterium avium infection. J Infect Chemother. 2004;10(3):185-188. [4]. Miyamoto H, et al. Synthesis and biological properties of substituted 1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acids. Bioorg Med Chem. 1995;3(12):1699-1706.

Additional Information

[1]. Efthymiopoulos C. Pharmacokinetics of grepafloxacin. J Antimicrob Chemother. 1997;40 Suppl A:35-43. [2]. Owen K. Comparative grepafloxacin phototoxicity in mouse skin. J Antimicrob Chemother. 1998;42(2):261-264. [3]. Cynamon MH, et al. The activity of grepafloxacin in two murine models of Mycobacterium avium infection. J Infect Chemother. 2004;10(3):185-188. [4]. Miyamoto H, et al. Synthesis and biological properties of substituted 1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acids. Bioorg Med Chem. 1995;3(12):1699-1706.

Frequently Asked Questions

What is the CAS number of Grepafloxacin?

The CAS number of Grepafloxacin is 119914-60-2.

What are the molecular formula and molecular weight of Grepafloxacin?

Grepafloxacin has molecular formula C19H22FN3O3 and molecular weight 359.39500 g/mol.

What are the upstream and downstream products of Grepafloxacin?

For Grepafloxacin, Upstream Products: 2-Methylpiperazine, 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acid.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Grepafloxacin (CAS 119914-60-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958905-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.