Docetaxel

多西他赛

Also known as: Taxotere, RP 56976, NSC 628503, N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol, N-debenzoyl-N-Boc-10-deacetyl taxol, Docetaxol, (2α,5β,7β,10β,13α)-4-Acetoxy-1,7,10-trihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate, Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

Docetaxel (CAS 114977-28-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C43H53NO14 and a molecular weight of 807.879 g/mol. It is also known as Taxotere, RP 56976 and NSC 628503. Key properties include a melting point of 186-192 °C (dec.), a boiling point of 900.5±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 498.4±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 114977-28-5
Jingsj CID: J-44333-7
Molecular Formula: C₄₃H₅₃NO₁₄
Chinese Name: 多西他赛
Molecular Weight: 807.879 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	186-192 °C (dec.)
Boiling Point	900.5±65.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	498.4±34.3 °C
Exact Mass	807.346619
PSA	224.45000
LogP	6.55
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.618

Activity & Biological Data

Target	Microtubule[1]
Additional Information	[1]. Attia RT, et al. The chemomodulatory effects of glufosfamide on docetaxel cytotoxicity in prostate cancer cells. PeerJ. 2016 Jun 29;4:e2168. [2]. Che CL, et al. DNA microarray reveals different pathways responding to paclitaxel and docetaxel in non-small cell lung cancer cell line. Int J Clin Exp Pathol. 2013 Jul 15;6(8):1538-48. [3]. Obi-Ioka Y, et al. Involvement of Wee1 in the circadian rhythm dependent intestinal damage induced by docetaxel. J Pharmacol Exp Ther. 2013 Oct;347(1):242-8. [4]. Li C, et al. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. J Pharm Biomed Anal. 2016 Sep 5;128:286-93.

Target

Microtubule[1]

Additional Information

[1]. Attia RT, et al. The chemomodulatory effects of glufosfamide on docetaxel cytotoxicity in prostate cancer cells. PeerJ. 2016 Jun 29;4:e2168. [2]. Che CL, et al. DNA microarray reveals different pathways responding to paclitaxel and docetaxel in non-small cell lung cancer cell line. Int J Clin Exp Pathol. 2013 Jul 15;6(8):1538-48. [3]. Obi-Ioka Y, et al. Involvement of Wee1 in the circadian rhythm dependent intestinal damage induced by docetaxel. J Pharmacol Exp Ther. 2013 Oct;347(1):242-8. [4]. Li C, et al. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. J Pharm Biomed Anal. 2016 Sep 5;128:286-93.

Customs & Trade Information

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Docetaxel?

The CAS number of Docetaxel is 114977-28-5.

What are the molecular formula and molecular weight of Docetaxel?

Docetaxel has molecular formula C43H53NO14 and molecular weight 807.879 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Docetaxel (CAS 114977-28-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44333-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.