Scopolamine hydrobromide

氢溴酸东莨菪碱

Also known as: Hyoscine hydrobromide, Scopolamine bromide, (-)-Scopolamine hydrobromide, Scopolamine hydrobromide (anhydrous), Scopolammonium bromide, l-Scopolamine hydrobromide, Scopolamine HBr, Hyoscine bromide, Atroscine hydrobromide

Scopolamine hydrobromide (CAS 114-49-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C17H22BrNO4 and a molecular weight of 384.265 g/mol. It is also known as Hyoscine hydrobromide, Scopolamine bromide and (-)-Scopolamine hydrobromide. Key properties include a melting point of 195-199 °C (dry matter)(lit.) and a boiling point of 460.3ºC at 760 mmHg. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 114-49-8
Jingsj CID: J-47473-5
Molecular Formula: C₁₇H₂₂BrNO₄
Chinese Name: 氢溴酸东莨菪碱
Molecular Weight: 384.265 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	195-199 °C (dry matter)(lit.)
Boiling Point	460.3ºC at 760 mmHg
Exact Mass	383.073212
PSA	62.30000
LogP	1.81410
Vapor Pressure	2.51E-10mmHg at 25°C
Additional Property	H2O: 50 mg/mL

Activity & Biological Data

Target	5-HT3 Receptor:2.09 μM (IC50) mAChR
Additional Information	[1]. Lochner M, et al. The muscarinic antagonists Scopolamine and atropine are competitive antagonists at 5-HT3 receptors. Neuropharmacology. 2016 Sep;108:220-8. [2]. O ET, et al. COGNITIVE-ENHANCING PROPERTIES OF MORINDA LUCIDA (RUBIACEAE) AND PELTOPHORUM PTEROCARPUM (FABACEAE) IN SCOPOLAMINE-INDUCED AMNESIC MICE. Afr J Tradit Complement Altern Med. 2017 Mar 1;14(3):136-141. [3]. Pattanashetti LA, et al. Evaluation of neuroprotective effect of Quercetin with Donepezil in Scopolamine-induced amnesia in rats. Indian J Pharmacol. 2017 Jan-Feb;49(1):60-64.

Target

5-HT3 Receptor:2.09 μM (IC50) mAChR

Additional Information

[1]. Lochner M, et al. The muscarinic antagonists Scopolamine and atropine are competitive antagonists at 5-HT3 receptors. Neuropharmacology. 2016 Sep;108:220-8. [2]. O ET, et al. COGNITIVE-ENHANCING PROPERTIES OF MORINDA LUCIDA (RUBIACEAE) AND PELTOPHORUM PTEROCARPUM (FABACEAE) IN SCOPOLAMINE-INDUCED AMNESIC MICE. Afr J Tradit Complement Altern Med. 2017 Mar 1;14(3):136-141. [3]. Pattanashetti LA, et al. Evaluation of neuroprotective effect of Quercetin with Donepezil in Scopolamine-induced amnesia in rats. Indian J Pharmacol. 2017 Jan-Feb;49(1):60-64.

Frequently Asked Questions

What is the CAS number of Scopolamine hydrobromide?

The CAS number of Scopolamine hydrobromide is 114-49-8.

What are the molecular formula and molecular weight of Scopolamine hydrobromide?

Scopolamine hydrobromide has molecular formula C17H22BrNO4 and molecular weight 384.265 g/mol.

What are the upstream and downstream products of Scopolamine hydrobromide?

For Scopolamine hydrobromide, Downstream Products: Oxitropium Bromide, Anisodamine, Hyoscyamine.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Scopolamine hydrobromide (CAS 114-49-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47473-5 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.