Chlorpheniramine maleate

马来酸氯苯那敏

Also known as: Chlorphenamine maleate, Chlorpheniramine Maleate, Chlorprophenpyridamine maleate, Chlortrimeton, Piriton, Teldrin, Allergisan, Histadur, Cloropiril, 1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane maleate, 2-[p-Chloro-α-(2-dimethylaminoethyl)benzyl]pyridine maleate, γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine (Z)-2-butenedioate (1:1)

Chlorpheniramine maleate (CAS 113-92-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C20H23ClN2O4 and a molecular weight of 390.861 g/mol. It is also known as Chlorphenamine maleate, Chlorpheniramine Maleate and Chlorprophenpyridamine maleate. Key properties include a melting point of 130-135 °C(lit.), a boiling point of 379.0±42.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 183.0±27.9 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
113-92-8
Jingsj CID
J-1114702-6
Molecular Formula
C20H23ClN2O4
Chinese Name
马来酸氯苯那敏
Molecular Weight
390.861 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point130-135 °C(lit.)
Boiling Point379.0±42.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point183.0±27.9 °C
Exact Mass390.134644
PSA90.73000
LogP3.39
Vapor Pressure0.0±0.9 mmHg at 25°C
Refractive Index1.565
Additional Property1-5 G/100 ML AT 21 ºC

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

Additional Information[1]. Medina, M.A., et al., Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines. Breast Cancer Res Treat, 1995. 35(2): p. 187-94. [2]. Kelly, J.X., et al., Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum. Antimicrob Agents Chemother, 2007. 51(11): p. 4133-40. [3]. Iemura, R., et al., Synthesis of 2-(4-substituted-1-piperazinyl)benzimidazoles as H1-antihistaminic agents. J Med Chem, 1986. 29(7): p. 1178-83. [4]. Takano, N., I. Arai, and M. Kurachi, Analysis of the spontaneous scratching behavior by NC/Nga mice: a possible approach to evaluate antipruritics for subjects with atopic dermatitis. Eur J Pharmacol, 2003. 471(3): p. 223-8.

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Chlorpheniramine maleate?

The CAS number of Chlorpheniramine maleate is 113-92-8.

What are the molecular formula and molecular weight of Chlorpheniramine maleate?

Chlorpheniramine maleate has molecular formula C20H23ClN2O4 and molecular weight 390.861 g/mol.

Is Chlorpheniramine maleate hazardous?

Chlorpheniramine maleate has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Chlorpheniramine maleate?

For Chlorpheniramine maleate, Downstream Products: Dexchlorpheniramine maleate, (R)-(-)-Chlorpheniramine maleate.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Chlorpheniramine maleate (CAS 113-92-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1114702-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.