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N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide

Also known as: TSQ, N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide, NSC 120213, Benzenesulfonamide, N-(6-methoxy-8-quinolinyl)-4-methyl-, N-(6-methoxy-8-quinolyl)-4-toluenesulfonamide, p-Toluenesulfonamide, N-(6-methoxy-8-quinolyl)-

N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide (CAS 109628-27-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C17H16N2O3S and a molecular weight of 328.38600 g/mol. Key properties include a melting point of 133–134 °C (lit.), a boiling point of 518.8ºC at 760mmHg, a density of 1.334g/cm3 and a flash point of 267.5 °C - closed cup (lit.). No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
109628-27-5
Jingsj CID
J-28345-2
Molecular Formula
C17H16N2O3S
Molecular Weight
328.38600 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point133–134 °C (lit.)
Boiling Point518.8ºC at 760mmHg
Density1.334g/cm3
Flash Point267.5 °C - closed cup (lit.)
Exact Mass328.08800
PSA76.67000
LogP4.50640
Vapor Pressure7.27E-11mmHg at 25°C
Refractive Index1.654

Activity & Biological Data

Additional Information[1]. Meeusen JW, et al. TSQ (6-methoxy-8-p-toluenesulfonamido-quinoline), a common fluorescent sensor for cellular zinc, images zinc proteins. Inorg Chem. 2011 Aug 15;50(16):7563-73.

Frequently Asked Questions

What is the CAS number of N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide?

The CAS number of N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide is 109628-27-5.

What are the molecular formula and molecular weight of N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide?

N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide has molecular formula C17H16N2O3S and molecular weight 328.38600 g/mol.

What are the upstream and downstream products of N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide?

For N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide, Upstream Products: 8-Amino-6-methoxyquinoline, p-Toluenesulfonyl chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide (CAS 109628-27-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28345-2 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.