Huperzine B

石杉碱乙

Also known as: 12-Methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one, (4aR,5R,10bR)-12-Methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one, 8,15-Didehydrolycodin-1(18H)-one, Fordimine, Huperzine B USP/EP/BP, Huperzine B-RM

Huperzine B (CAS 103548-82-9) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C16H20N2O and a molecular weight of 256.343 g/mol. It is also known as 12-Methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one, (4aR,5R,10bR)-12-Methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one and 8,15-Didehydrolycodin-1(18H)-one. Key properties include a boiling point of 533.5±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 216.4±30.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
103548-82-9
Jingsj CID
J-1963142-6
Molecular Formula
C16H20N2O
Chinese Name
石杉碱乙
Molecular Weight
256.343 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point533.5±50.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point216.4±30.3 °C
Exact Mass256.157562
PSA44.89000
LogP1.98
Vapor Pressure0.0±1.4 mmHg at 25°C
Refractive Index1.624

Activity & Biological Data

TargetAChE[1]
Additional Information[1]. Zhang HY, et al. Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cells. Neurosci Lett. 2000 Sep 29;292(1):41-4. [2]. He XC, et al. Study on dual-site inhibitors of acetylcholinesterase: Highly potent derivatives of bis- and bifunctional huperzine B. Bioorg Med Chem. 2007 Feb 1;15(3):1394-408.

Frequently Asked Questions

What is the CAS number of Huperzine B?

The CAS number of Huperzine B is 103548-82-9.

What are the molecular formula and molecular weight of Huperzine B?

Huperzine B has molecular formula C16H20N2O and molecular weight 256.343 g/mol.

What are the upstream and downstream products of Huperzine B?

For Huperzine B, Upstream Products: Pulegone; Downstream Products: 7-Methylquinoline, 2-Hydroxy-6-methylpyridine.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Huperzine B (CAS 103548-82-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963142-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.