Glibenclamide

格列本脲

Also known as: Glyburide, Glybenzcyclamide, Micronase, Daonil, Euglucon, Diabeta, Glynase, 5-Chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide

Glibenclamide (CAS 10238-21-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C23H28ClN3O5S and a molecular weight of 494.004 g/mol. It is also known as Glyburide, Glybenzcyclamide and Micronase. Key properties include a melting point of 173-175°C, a boiling point of 705.7±70.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 380.6±35.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 10238-21-8
Jingsj CID: J-1098105-4
Molecular Formula: C₂₃H₂₈ClN₃O₅S
Chinese Name: 格列本脲
Molecular Weight: 494.004 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	173-175°C
Boiling Point	705.7±70.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	380.6±35.7 °C
Exact Mass	493.143829
PSA	121.98000
LogP	5.19
Vapor Pressure	0.0±2.4 mmHg at 25°C
Refractive Index	1.623

Activity & Biological Data

Additional Information	[1]. Núnez M, Medina V, Cricco G, et al. Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231. BMC Pharmacol Toxicol. 2013 Jan 11;14(1):6. [2]. Soydan N, Bretzel RG, Fischer B, et al. Reduced capacity of heart rate regulation in response to mild hypoglycemia induced by glibenclamide and physical exercise in type 2 diabetes. Metabolism. 2013 Jan 11. pii: S0026-0495(12)00456-8. [3]. Sokolovska J, Isajevs S, Sugoka O, et al. Comparison of the Effects of Glibenclamide on Metabolic Parameters, GLUT1 Expression, and Liver Injury in Rats With Severe and Mild Streptozotocin-Induced Diabetes Mellitus. Medicina (Kaunas). 2012;48(10):532-43. [4]. Gangji AS, Cukierman T, Gerstein HC et al. A systematic review and meta-analysis of hypoglycemia and cardiovascular events: a comparison of glyburide with other secretagogues and with insulin. Diabetes Care. 2007 Feb;30(2):389-94.

Additional Information

[1]. Núnez M, Medina V, Cricco G, et al. Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231. BMC Pharmacol Toxicol. 2013 Jan 11;14(1):6. [2]. Soydan N, Bretzel RG, Fischer B, et al. Reduced capacity of heart rate regulation in response to mild hypoglycemia induced by glibenclamide and physical exercise in type 2 diabetes. Metabolism. 2013 Jan 11. pii: S0026-0495(12)00456-8. [3]. Sokolovska J, Isajevs S, Sugoka O, et al. Comparison of the Effects of Glibenclamide on Metabolic Parameters, GLUT1 Expression, and Liver Injury in Rats With Severe and Mild Streptozotocin-Induced Diabetes Mellitus. Medicina (Kaunas). 2012;48(10):532-43. [4]. Gangji AS, Cukierman T, Gerstein HC et al. A systematic review and meta-analysis of hypoglycemia and cardiovascular events: a comparison of glyburide with other secretagogues and with insulin. Diabetes Care. 2007 Feb;30(2):389-94.

Customs & Trade Information

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Glibenclamide?

The CAS number of Glibenclamide is 10238-21-8.

What are the molecular formula and molecular weight of Glibenclamide?

Glibenclamide has molecular formula C23H28ClN3O5S and molecular weight 494.004 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Glibenclamide (CAS 10238-21-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1098105-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.