Zardaverine

扎达维林

Also known as: 3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-, 3-[4-(difluoromethoxy)-3-methoxy-phenyl]-1H-pyridazin-6-one, 3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one, 6-(4-(Difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one, 6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone, 6-[4-(Difluoromethoxy)-3-methoxyphenyl]pyridazin-3(2H)-one, Zardavenine, zardaverina, zardaverinum

Zardaverine (CAS 101975-10-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H10F2N2O3 and a molecular weight of 268.216 g/mol. It is also known as 3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-, 3-[4-(difluoromethoxy)-3-methoxy-phenyl]-1H-pyridazin-6-one and 3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one. Key property: a density of 1.4±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 101975-10-4
Jingsj CID: J-12291-5
Molecular Formula: C₁₂H₁₀F₂N₂O₃
Chinese Name: 扎达维林
Molecular Weight: 268.216 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.4±0.1 g/cm3
Exact Mass	268.065948
PSA	64.21000
LogP	0.90
Refractive Index	1.555
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. R.T. Schermuly, H. Leuchte, H.A. Ghofrani, et al. Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure. ERJ, 2003 ,22 (2): 342-347. [2]. D. Ukena, K. Rentz, C. Reiber, et al. Effects of the mixed phosphodiesterase III/IV inhibitor, zardaverine, on airway function in patients with chronic airflow obstruction. Respiratory Medicine.1995, 89 ( 6) : 441-444. [3]. Schade FU, Schudt C. The specific type III and IV phosphodiesterase inhibitor zardaverine suppresses formation of tumor necrosis factor by macrophages. European Journal of Pharmacology.1993, 230(1):9-14.

Additional Information

[1]. R.T. Schermuly, H. Leuchte, H.A. Ghofrani, et al. Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure. ERJ, 2003 ,22 (2): 342-347. [2]. D. Ukena, K. Rentz, C. Reiber, et al. Effects of the mixed phosphodiesterase III/IV inhibitor, zardaverine, on airway function in patients with chronic airflow obstruction. Respiratory Medicine.1995, 89 ( 6) : 441-444. [3]. Schade FU, Schudt C. The specific type III and IV phosphodiesterase inhibitor zardaverine suppresses formation of tumor necrosis factor by macrophages. European Journal of Pharmacology.1993, 230(1):9-14.

Frequently Asked Questions

What is the CAS number of Zardaverine?

The CAS number of Zardaverine is 101975-10-4.

What are the molecular formula and molecular weight of Zardaverine?

Zardaverine has molecular formula C12H10F2N2O3 and molecular weight 268.216 g/mol.

What are the upstream and downstream products of Zardaverine?

For Zardaverine, Upstream Products: Apocynin.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Zardaverine (CAS 101975-10-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-12291-5 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.