Butenafine hydrochloride

盐酸布替萘芬

Also known as: Butenafine HCl, Butenafine, Mentax, KP-363, N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride, N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride

Butenafine hydrochloride (CAS 101827-46-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C23H28ClN and a molecular weight of 353.93 g/mol. It is also known as Butenafine HCl, Butenafine and Mentax. Key properties include a melting point of 210-214°C, a boiling point of 426.1±14.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 187.7±17.0 °C. It is classified under GHS with signal word Warning and hazard statements H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 101827-46-7
Jingsj CID: J-11414-1
Molecular Formula: C₂₃H₂₈ClN
Chinese Name: 盐酸布替萘芬
Molecular Weight: 353.93 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	210-214°C
Boiling Point	426.1±14.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	187.7±17.0 °C
PSA	3.24000
LogP	6.77
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.598
Storage Conditions	Refrigerator, Under Inert Atmosphere

GHS Safety & Compliance

IrritantSignal word: Warning

H312 — Harmful in contact with skin

Activity & Biological Data

Additional Information	[1]. Singal A. Butenafine and superficial mycoses: current status. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005. [2]. Kokjohn K, Bradley M, Griffiths B, Ghannoum M. Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria. Int J Dermatol. 2003 Sep;42 Suppl 1:11-7. [3]. Syed TA, Maibach HI. Butenafine hydrochloride: for the treatment of interdigital tinea pedis. Expert Opin Pharmacother. 2000 Mar;1(3):467-73. [4]. McNeely W, Spencer CM. Butenafine. Drugs. 1998 Mar;55(3):405-12; discussion 413. [5]. Butenafine

Additional Information

[1]. Singal A. Butenafine and superficial mycoses: current status. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005. [2]. Kokjohn K, Bradley M, Griffiths B, Ghannoum M. Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria. Int J Dermatol. 2003 Sep;42 Suppl 1:11-7. [3]. Syed TA, Maibach HI. Butenafine hydrochloride: for the treatment of interdigital tinea pedis. Expert Opin Pharmacother. 2000 Mar;1(3):467-73. [4]. McNeely W, Spencer CM. Butenafine. Drugs. 1998 Mar;55(3):405-12; discussion 413. [5]. Butenafine

Customs & Trade Information

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Butenafine hydrochloride?

The CAS number of Butenafine hydrochloride is 101827-46-7.

What are the molecular formula and molecular weight of Butenafine hydrochloride?

Butenafine hydrochloride has molecular formula C23H28ClN and molecular weight 353.93 g/mol.

Is Butenafine hydrochloride hazardous?

Butenafine hydrochloride has GHS signal word Warning and hazard statements H312 — Harmful in contact with skin.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Butenafine hydrochloride (CAS 101827-46-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-11414-1 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.