1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid
1-苄基-3-叔丁基-1H-吡唑-5-羧酸
Also known as: SORT-PGRN interaction inhibitor 1, 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid, 95+%, 1H-Pyrazole-5-carboxylic acid, 3-(1,1-dimethylethyl)-1-(phenylmethyl)-, 2-Benzyl-5-tert-butyl-2H-pyrazole-3-carboxylic acid, 2-benzyl-5-tert-butyl-2H-pyrazole-3-carboxylic acid, 2-benzyl-5-tert-butylpyrazole-3-carboxylic acid, BUTTPARK 153\57-04
1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid (CAS 100957-85-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C15H18N2O2 and a molecular weight of 258.31600 g/mol. It is also known as SORT-PGRN interaction inhibitor 1, 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid, 95+% and 1H-Pyrazole-5-carboxylic acid, 3-(1,1-dimethylethyl)-1-(phenylmethyl)-. Key properties include a melting point of 126ºC, a boiling point of 438.4ºC at 760 mmHg, a density of 1.12g/cm3 and a flash point of 218.9ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 100957-85-5
- Jingsj CID
- J-1981388-8
- Molecular Formula
- C15H18N2O2
- Chinese Name
- 1-苄基-3-叔丁基-1H-吡唑-5-羧酸
- Molecular Weight
- 258.31600 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 126ºC |
|---|---|
| Boiling Point | 438.4ºC at 760 mmHg |
| Density | 1.12g/cm3 |
| Flash Point | 218.9ºC |
| Exact Mass | 258.13700 |
| PSA | 55.12000 |
| LogP | 2.92710 |
| Vapor Pressure | 1.85E-08mmHg at 25°C |
| Refractive Index | 1.568 |
Activity & Biological Data
| Target | IC50: 2 μM (Sortilin-progranulin interaction)[1] |
|---|---|
| Additional Information | [1]. Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403. |
Customs & Trade Information
| HS Code | 2933199090 |
|---|---|
| Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid?
The CAS number of 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid is 100957-85-5.
What are the molecular formula and molecular weight of 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid?
1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid has molecular formula C15H18N2O2 and molecular weight 258.31600 g/mol.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid (CAS 100957-85-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981388-8 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.