Trigonelline
Also known as: Trigonellin, Caffearine, Coffearin, Coffearine, Gynesine, Gynesis, N-Methylnicotinate, N-methyl-3-carboxypyridinium, 1-Methylpyridinium-3-carboxylate, 1-methylpyridinium-3-carbonate, Betain nicotinate, Nicotinic acid N-methylbetaine, 1-Methyl-3-pyridiniumcarboxylate, Pyridinium, 3-carboxy-1-methyl-, inner salt, Trigenolline, betainnicotinate, nicotinicacidn-methylbetaine
Trigonelline (CAS 535-83-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C7H7NO2 and a molecular weight of 137.136 g/mol. Key properties include a melting point of 260ºC (dec.), a boiling point of 251.96°C (rough estimate) and a density of 1.2528 (rough estimate). No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 535-83-1
- Jingsj CID
- J-9893-1
- Molecular Formula
- C7H7NO2
- Molecular Weight
- 137.136 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 260ºC (dec.) |
|---|---|
| Boiling Point | 251.96°C (rough estimate) |
| Density | 1.2528 (rough estimate) |
| Exact Mass | 137.047684 |
| PSA | 44.01000 |
| LogP | -3.91 |
| Refractive Index | 1.554 |
| Storage Conditions | 2~8℃ |
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Ilavenil S, et al. Trigonelline protects the cardiocyte from hydrogen peroxide induced apoptosis in H9c2 cells. Asian Pac J Trop Med. 2015 Apr;8(4):263-8. [2]. Joanna Folwarczna, et al. Effects of Trigonelline, an Alkaloid Present in Coffee, on Diabetes-Induced Disorders in the Rat Skeletal System. Nutrients. 2016 Mar; 8(3): 133. |
Frequently Asked Questions
What is the CAS number of Trigonelline?
The CAS number of Trigonelline is 535-83-1.
What are the molecular formula and molecular weight of Trigonelline?
Trigonelline has molecular formula C7H7NO2 and molecular weight 137.136 g/mol.
What are the upstream and downstream products of Trigonelline?
For Trigonelline, Upstream Products: 1-Methylpyrrole, Carbon dioxide, Carbon; Downstream Products: 1-Methylpiperidine, 1-methylpiperidine-3-carboxylic acid, Arecaidine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Trigonelline (CAS 535-83-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-9893-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.