Nilvadipine
Also known as: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(1-Methylethyl) Ester, 5-Isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, FK235, FR34235, Escor, Nivadil, SKF-102362, BAY-e-6927, 5-Isopropyl-3-methyl-2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, 3,5-Pyridinedicarboxylic acid, 2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester
Nilvadipine (CAS 75530-68-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H19N3O6 and a molecular weight of 385.371 g/mol. Key properties include a melting point of 148-150ºC, a boiling point of 526.7±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 272.3±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 75530-68-6
- Jingsj CID
- J-9636-6
- Molecular Formula
- C19H19N3O6
- Molecular Weight
- 385.371 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 148-150ºC |
|---|---|
| Boiling Point | 526.7±50.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 272.3±30.1 °C |
| Exact Mass | 385.127380 |
| PSA | 134.24000 |
| LogP | 1.72 |
| Vapor Pressure | 0.0±1.4 mmHg at 25°C |
| Refractive Index | 1.584 |
| Storage Conditions | -20°C Freezer |
| Additional Property | DMSO: soluble15mg/mL, clear |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Target | IC50: 0.1 nM (Calcium channel)[1] |
|---|---|
| Additional Information | [1]. Nomoto A, et al. Smooth muscle cell migration induced by inflammatory cell products and its inhibition by a potent calcium antagonist, Nilvadipine. Atherosclerosis. 1988 Aug;72(2-3):213-9. [2]. Nomoto A, et al. Antiatherogenic activity of FR34235 (Nilvadipine), a new potent calcium antagonist. Effect on cuff-induced intimal thickening of rabbit carotid artery. Atherosclerosis. 1987 Apr;64(2-3):255-61. [3]. Sugawara H, et al. Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation. Hypertens Res. 1996 Dec;19(4):223-8. [4]. Yamazaki H, et al. Preservation of retinal morphology and functions in royal college surgeons rat by Nilvadipine, a Ca(2+) antagonist. Invest Ophthalmol Vis Sci. 2002 Apr;43(4):919-26. |
Frequently Asked Questions
What is the CAS number of Nilvadipine?
The CAS number of Nilvadipine is 75530-68-6.
What are the molecular formula and molecular weight of Nilvadipine?
Nilvadipine has molecular formula C19H19N3O6 and molecular weight 385.371 g/mol.
Is Nilvadipine hazardous?
Nilvadipine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Nilvadipine?
For Nilvadipine, Upstream Products: sodium carbonate, 5-Isopropyl-3-methyl 2-formyl-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, isopropyl acetoacetate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Nilvadipine (CAS 75530-68-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-9636-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.