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4-Chloro-2-methoxyphenol

Also known as: 4-Chloroguaiacol, Phenol, 4-chloro-2-methoxy-, 5-Chloro-2-hydroxyanisole, 4-Chloropyrocatechol monomethyl ether, 2-Methoxy-4-chlorophenol

4-Chloro-2-methoxyphenol (CAS 16766-30-6) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C7H7ClO2 and a molecular weight of 158.582 g/mol. Key properties include a melting point of 16-17 °C(lit.), a boiling point of 242.4±20.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 100.4±21.8 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
16766-30-6
Jingsj CID
J-9482-6
Molecular Formula
C7H7ClO2
Molecular Weight
158.582 g/mol
Category
Alcohols
Last updated
8/21/2026

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Physicochemical Properties

Melting Point16-17 °C(lit.)
Boiling Point242.4±20.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point100.4±21.8 °C
Exact Mass158.013458
PSA29.46000
LogP2.36
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.554

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Patrícia Fontes Pinheiro,, et al. Semisynthetic Phenol Derivatives Obtained from Natural Phenols: Antimicrobial Activity and Molecular Properties. J Agric Food Chem. 2018 Jan 10;66(1):323-330.

Customs & Trade Information

HS Code2909500000
Summary2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4-Chloro-2-methoxyphenol?

The CAS number of 4-Chloro-2-methoxyphenol is 16766-30-6.

What are the molecular formula and molecular weight of 4-Chloro-2-methoxyphenol?

4-Chloro-2-methoxyphenol has molecular formula C7H7ClO2 and molecular weight 158.582 g/mol.

Is 4-Chloro-2-methoxyphenol hazardous?

4-Chloro-2-methoxyphenol has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 4-Chloro-2-methoxyphenol?

For 4-Chloro-2-methoxyphenol, Upstream Products: Guaiacol, 2-Aminopyridine, 4-Chloro-2-methoxyaniline; Downstream Products: Eugenol, 4-Chloro-1,2-dimethoxybenzene, 4,6-Dichloroguaiacol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Chloro-2-methoxyphenol (CAS 16766-30-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-9482-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.