Selinexor

Also known as: KPT-330, KPT330, XPOVIO, (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide, (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide, UNII-31TZ62FO8F

Selinexor (CAS 1393477-72-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H11F6N7O and a molecular weight of 443.306 g/mol. Key property: a density of 1.6±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1393477-72-9
Jingsj CID: J-90033-4
Molecular Formula: C₁₇H₁₁F₆N₇O
Molecular Weight: 443.306 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.6±0.1 g/cm3
Exact Mass	443.092926
PSA	97.62000
LogP	3.62
Refractive Index	1.594
Storage Conditions	-20℃

Activity & Biological Data

Additional Information	[1]. Etchin J, et al. KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. Br J Haematol. 2013 Apr;161(1):117-27. [2]. Tai YT, et al. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications. Leukemia. 2014 Jan;28(1):155-65.

Additional Information

[1]. Etchin J, et al. KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. Br J Haematol. 2013 Apr;161(1):117-27. [2]. Tai YT, et al. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications. Leukemia. 2014 Jan;28(1):155-65.

Frequently Asked Questions

What is the CAS number of Selinexor?

The CAS number of Selinexor is 1393477-72-9.

What are the molecular formula and molecular weight of Selinexor?

Selinexor has molecular formula C17H11F6N7O and molecular weight 443.306 g/mol.

What are the upstream and downstream products of Selinexor?

For Selinexor, Upstream Products: 2-Hydrazinopyrazine, 3,5-Bis(trifluoromethyl)benzonitrile, 3,5-bis(trifluoromethyl)thiobenzamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Selinexor (CAS 1393477-72-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-90033-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.